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Array Comparative Genomic Hybridization

Protocols and Applications

  • Book
  • © 2013

Overview

Editors:
  1. Diponkar Banerjee

    1. , Dept. of Pathology & Lab. Medicine, The Ottawa Hospital, Ottawa, Canada

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Sohrab P. Shah

    1. , Dept. of Molecular Oncology, BC Cancer Agency, Vancouver, Canada

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
  • Includes supplementary material: sn.pub/extras

Part of the book series: Methods in Molecular Biology (MIMB, volume 973)

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Table of contents (22 protocols)

  1. Front Matter

    Pages i-xii
    Download chapter PDF

  2. Array Comparative Genomic Hybridization: An Overview of Protocols, Applications, and Technology Trends

    • Diponkar Banerjee
    Pages 1-13

  3. Ultradense Array CGH and Discovery of Micro-Copy Number Alterations and Gene Fusions in the Cancer Genome

    • Ewa Przybytkowski, Adriana Aguilar-Mahecha, Sheida Nabavi, Peter J. Tonellato, Mark Basik
    Pages 15-38

  4. Epigenomics: Sequencing the Methylome

    • Martin Hirst
    Pages 39-54

  5. Application of Array Comparative Genomic Hybridization in Chronic Myeloid Leukemia

    • Seonyang Park, Youngil Koh, Seung-Hyun Jung, Yeun-Jun Chung
    Pages 55-68

  6. The Use of Cytogenetic Microarrays in Myelodysplastic Syndrome Characterization

    • Lisa G. Shaffer, Blake C. Ballif, Roger A. Schultz
    Pages 69-85

  7. CGH Protocols: Chronic Lymphocytic Leukemia

    • Esteban Braggio, Rafael Fonseca, Neil E. Kay
    Pages 87-98

  8. Analysis of Acquired Genomic Copy Number Aberrations and Regions of Loss of Heterozygosity in Acute Myelogenous Leukemia Genomes Using Affymetrix SNP 6.0 Arrays and Supporting Software Tools

    • Peter D. Ouillette, Kerby A. Shedden, Cheng Li, Sami N. Malek
    Pages 99-119

  9. Clinical Applications of BAC Array-CGH to the Study of Diffuse Large B-Cell Lymphomas

    • Cristina Robledo, Juan Luis García, Jesús M. Hernández
    Pages 121-145

  10. Genomic Profiling of Mantle Cell Lymphoma

    • Melissa Rieger Menanteau, Jose A. Martinez-Climent
    Pages 147-163

  11. Copy Number Analysis in EBV-Positive Nodal Peripheral T Cell Lymphoma, Unspecified

    • Kyusam Choi, Hyunjeong Ju, Young Hyeh Ko
    Pages 165-174

  12. Mycosis Fungoides and Sézary Syndrome

    • Blanca Espinet, Rocío Salgado
    Pages 175-188

  13. Array CGH Reveals Clonal Evolution of Adult T-Cell Leukemia/Lymphoma

    • Akira Umino, Masao Seto
    Pages 189-196

  14. Array-CGH Analysis of Cutaneous Anaplastic Large Cell Lymphoma

    • K. Szuhai, R. van Doorn, C. P. Tensen, Van Kester
    Pages 197-212

  15. Genome-Wide DNA Profiling of HIV-Related B-Cell Lymphomas

    • Andrea Rinaldi, Daniela Capello, Emanuele Zucca, Gianluca Gaidano, Francesco Bertoni
    Pages 213-226

  16. Array Comparative Genomic Hybridization in Osteosarcoma

    • Bekim Sadikovic, Paul C. Park, Shamini Selvarajah, Maria Zielenska
    Pages 227-247

  17. Comparative Genomic Hybridization of Wilms’ tumor

    • Shahrad Rod Rassekh, Evica Rajcan-Separovic
    Pages 249-265

  18. Array-CGH in Childhood MDS

    • Marcel Tauscher, Inka Praulich, Doris Steinemann
    Pages 267-278

  19. Nonfamilial Breast Cancer Subtypes

    • Markus Ringnér, Johan Staaf, Göran Jönsson
    Pages 279-295

  20. Applications of Array-CGH for Lung Cancer

    • Kenneth J. Craddock, Wan L. Lam, Ming-Sound Tsao
    Pages 297-324
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Keywords

About this book

The earliest descriptions of human chromosomes initiated the genomics revolution that is now upon us. Array Comparative Genomic Hybridization: Protocols and Applications explores the scope of what is now possible as far as documenting abnormalities associated with several human cancers. While the technology for interrogating the human genome continues to evolve, refinement of comparative genomic hybridization (CGH) using array CGH and related technologies have provided enormous insight into human cancers at an affordable scale. Written in the successful Methods in Molecular Biologyâ„¢ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.

 

Authoritative and easily accessible, Array Comparative Genomic Hybridization: Protocols and Applications provides researchers with well-honed methodologies to learn these techniques for their own use in research or clinical diagnostic laboratories.

Editors and Affiliations

  • , Dept. of Pathology & Lab. Medicine, The Ottawa Hospital, Ottawa, Canada

    Diponkar Banerjee

  • , Dept. of Molecular Oncology, BC Cancer Agency, Vancouver, Canada

    Sohrab P. Shah

Bibliographic Information

  • Book Title: Array Comparative Genomic Hybridization

  • Book Subtitle: Protocols and Applications

  • Editors: Diponkar Banerjee, Sohrab P. Shah

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-62703-281-0

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media, LLC 2013

  • Hardcover ISBN: 978-1-62703-280-3Published: 15 February 2013

  • Softcover ISBN: 978-1-4939-5955-6Published: 23 August 2016

  • eBook ISBN: 978-1-62703-281-0Published: 15 February 2013

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: XII, 382

  • Topics: Human Genetics, Laboratory Medicine

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