Overview
- Features cutting-edge approaches to studying brain neurochemistry in vivo, with regard to physiology, psychopharmacology, drug metabolism, and pathology
- Includes detailed guidance and practical tips for successfully implementing the microdialysis techniques both animals and humans
- Features clear, step-by-step techniques, written by highly respected and innovative experts, proven successful in laboratories around the world
- Includes supplementary material: sn.pub/extras
Part of the book series: Neuromethods (NM, volume 75)
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Table of contents (16 protocols)
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Front Matter
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Back Matter
Keywords
About this book
Since its first application, microdialysis has become incredibly popular to study brain function and has been applied with success in different fields from psychopharmacology, neurobiology, and physiology in animals and also humans. Microdialysis Techniques in Neuroscience focuses on the practical aspects of microdialysis in animal and human, highlighting current technical limitations and providing a vision of what is yet to come for the determination of the most disparate compounds in the brain. The book’s contents range from new techniques for detection and quantifying the release of several different neurotransmitters in vitro and in vivo, even in freely moving animals, to sophisticated use of reverse dialysis and the application of microdialysis in pharmacokinetic studies. Each of the sixteen chapters, in fitting with the spirit of the Neuromethods series, contain an introduction that gives a broad overview of a focused topic, followed by an extensive protocol on how the experiments are performed along with invaluable practical advice.
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Detailed and authoritative, Microdialysis Techniques in Neuroscience will be a valuable reference for students, neuroscientists, and physicians for the use of microdialysis in the study of brain functions and its clinical applications.
Editors and Affiliations
Bibliographic Information
Book Title: Microdialysis Techniques in Neuroscience
Editors: Giuseppe Di Giovanni, Vincenzo Di Matteo
Series Title: Neuromethods
DOI: https://doi.org/10.1007/978-1-62703-173-8
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC 2013
Hardcover ISBN: 978-1-62703-172-1Published: 06 November 2012
Softcover ISBN: 978-1-4939-5814-6Published: 23 August 2016
eBook ISBN: 978-1-62703-173-8Published: 06 November 2012
Series ISSN: 0893-2336
Series E-ISSN: 1940-6045
Edition Number: 1
Number of Pages: XVII, 341
Topics: Neurosciences, Neurobiology