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  • © 2012

Quantitative Trait Loci (QTL)

Methods and Protocols

Editors:

  • A practical resource for researchers interested in link between phenotypic and genotypic variation
  • Provides step-by-step detail essentail for reproducible results
  • Contains key notes and implementation advice from the experts

Part of the book series: Methods in Molecular Biology (MIMB, volume 871)

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Table of contents (16 protocols)

  1. Front Matter

    Pages i-xi
  2. Setting Up Mapping Populations

    1. Front Matter

      Pages 1-1
    2. Backcross Populations and Near Isogenic Lines

      • Rik Kooke, Erik Wijnker, Joost J. B. Keurentjes
      Pages 3-16
    3. F2 Designs for QTL Analysis

      • Yuan-Ming Zhang
      Pages 17-29
    4. Two Flavors of Bulk Segregant Analysis in Yeast

      • Maitreya J. Dunham
      Pages 41-54
    5. Selecting Markers and Evaluating Coverage

      • Matthew A. Cleveland, Nader Deeb
      Pages 55-71
  3. Identifying Quantitative Trait Loci

    1. Front Matter

      Pages 73-73
    2. Meta-analysis of QTL Mapping Experiments

      • Xiao-Lin Wu, Zhi-Liang Hu
      Pages 145-171
  4. Extending the Power of Quantitative Trait Locus Analysis

    1. Front Matter

      Pages 173-173
    2. Estimation and Interpretation of Genetic Effects with Epistasis Using the NOIA Model

      • José M. Álvarez-Castro, Örjan Carlborg, Lars Rönnegård
      Pages 191-204
    3. Identifying QTL for Multiple Complex Traits in Experimental Crosses

      • Samprit Banerjee, Nengjun Yi
      Pages 205-225
    4. Functional Mapping of Developmental Processes: Theory, Applications, and Prospects

      • Kiranmoy Das, Zhongwen Huang, Jingyuan Liu, Guifang Fu, Jiahan Li, Yao Li et al.
      Pages 227-243
    5. Statistical Models for Genetic Mapping in Polyploids: Challenges and Opportunities

      • Jiahan Li, Kiranmoy Das, Jingyuan Liu, Guifang Fu, Yao Li, Christian Tobias et al.
      Pages 245-261
  5. Case Studies

    1. Front Matter

      Pages 263-263
    2. eQTL

      • Lun Li, Xianghua Zhang, Hongyu Zhao
      Pages 265-279

About this book

Over the last two decades advances in genotyping technology, and the development of quantitative genetic analytical techniques have made it possible to dissect complex traits and link quantitative variation in traits to allelic variation on chromosomes or quantitative trait loci (QTLs). In Quantitative Trait Loci (QTLs):Methods and Protocols, expert researchers in the field detail methods and techniques that focus on specific components of the entire process of quantitative train loci experiments. These include methods and techniques for the mapping populations, identifying quantitative trait loci, extending the power of quantitative trait locus analysis, and case studies. Written in the highly successful Methods in Molecular Biology™ series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory.

 

Thorough and intuitive, Quantitative Trait Loci (QTLs):Methods and Protocols aids scientists in the further study of the links between phenotypic and genotypic variation in fields from medicine to agriculture, from molecular biology to evolution to ecology.

Editors and Affiliations

  • University of California, San Diego, La Jolla, USA

    Scott A. Rifkin

Bibliographic Information

  • Book Title: Quantitative Trait Loci (QTL)

  • Book Subtitle: Methods and Protocols

  • Editors: Scott A. Rifkin

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-61779-785-9

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media New York 2012

  • Hardcover ISBN: 978-1-61779-784-2Published: 09 May 2012

  • Softcover ISBN: 978-1-4939-5832-0Published: 23 August 2016

  • eBook ISBN: 978-1-61779-785-9Published: 08 May 2012

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: XI, 331

  • Topics: Human Genetics

Buy it now

Buying options

eBook USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access