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Methods in Molecular Biology

Nanopore-Based Technology

Editors: Gracheva, Maria E. (Ed.)

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  • Provides a good representation of present-day available techniques for biomolecule characterization with nanoporous membranes
  • Includes many step-by-step, easy to follow protocols
  • Features tips from the experts to ensure successful implementation
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eBook $109.00
price for USA in USD
  • ISBN 978-1-61779-773-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
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  • Immediate eBook download after purchase
Hardcover $139.99
price for USA in USD
Softcover $139.99
price for USA in USD
About this book

Nanopores are vital biological features, described as tiny holes in cellular membranes used for recognition and transport of ions and molecules between compartments within the cell, as well as between the extracellular environment and the cell itself. Their study, ever growing in esteem, leads toward the promise of ultra-fast sequencing of DNA molecules with the ultimate goal of building a nanoscale device that will make rapid and cheap DNA sequencing a reality.  In Nanopore-Based Technology, expert researchers in the forefront of the field explore the cutting-edge of nanopore technology for single molecule sensing, detection, and characterization.  Divided into four convenient parts, this volume covers single molecule characterization techniques utilizing biological pores, methods for biomolecule characterization with nanoporous artificial membranes, computational studies of the biomolecule confined within the nanopore environment, as well as techniques that use novel materials in conjunction with nanopore sensing.  Written for the highly successful Methods in Molecular Biology™ series, this work provides the kind of detailed description and implementation advice that is crucial for achieving optimal results.

 

Authoritative and state-of-the-art, Nanopore-Based Technology serves as an excellent representation of the present-day available techniques for biomolecule characterization with nanoporous membranes in order to guide researchers toward developing the next generation of technologies for fast and cheap DNA sequencing with practically no limitations on the read lengths.

Table of contents (14 chapters)

Table of contents (14 chapters)
  • Detecting and Characterizing Individual Molecules with Single Nanopores

    Pages 3-20

    Kasianowicz, John J. (et al.)

  • Protein Sensing with Engineered Protein Nanopores

    Pages 21-37

    Mohammad, Mohammad M. (et al.)

  • Measurements of DNA Immobilized in the Alpha-Hemolysin Nanopore

    Pages 39-53

    Purnell, Robert (et al.)

  • DNA Unzipping and Protein Unfolding Using Nanopores

    Pages 55-75

    Merstorf, Céline (et al.)

  • DNA Characterization with Ion Beam-Sculpted Silicon Nitride Nanopores

    Pages 79-97

    Rollings, Ryan C. (et al.)

Buy this book

eBook $109.00
price for USA in USD
  • ISBN 978-1-61779-773-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $139.99
price for USA in USD
Softcover $139.99
price for USA in USD
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Bibliographic Information

Bibliographic Information
Book Title
Nanopore-Based Technology
Editors
  • Maria E. Gracheva
Series Title
Methods in Molecular Biology
Series Volume
870
Copyright
2012
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-61779-773-6
DOI
10.1007/978-1-61779-773-6
Hardcover ISBN
978-1-61779-772-9
Softcover ISBN
978-1-4939-5809-2
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XI, 267
Topics