Methods in Molecular Biology

Exon Skipping

Methods and Protocols

Editors: Aartsma-Rus, Annemieke (Ed.)

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  • Provides an overview of the exon skipping field
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
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  • ISBN 978-1-61779-767-5
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About this book

“Next generation” sequencing techniques allow for more detailed analysis of exons and introns in multiple genes at the same time. This will reveal many mutations that potentially lead to exon skipping. To functionally test these a lot can be achieved with a limited set of protocols, while for the intentional induction of exon skipping different tools and target genes are involved and the translational path from in vitro splicing to in vivo tests in animal models requiring a more extensive set of protocols. Exon Skipping: Methods and Protocols provides scientist with a comprehensive guide to many of the methods and techniques used for exon skipping, such as methods on how to discriminate “real polymorphisms” from mutations that affect splicing. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical Exon Skipping: Methods and Protocols seeks to aid scientists in the continuing study of exon skipping.

Table of contents (27 chapters)

Table of contents (27 chapters)

Buy this book

eBook $139.00
price for USA in USD
  • ISBN 978-1-61779-767-5
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase Institutional customers should get in touch with their account manager
Hardcover $219.99
price for USA in USD
Softcover $179.00
price for USA in USD
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Bibliographic Information

Bibliographic Information
Book Title
Exon Skipping
Book Subtitle
Methods and Protocols
Editors
  • Annemieke Aartsma-Rus
Series Title
Methods in Molecular Biology
Series Volume
867
Copyright
2012
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media,LLC
eBook ISBN
978-1-61779-767-5
DOI
10.1007/978-1-61779-767-5
Hardcover ISBN
978-1-61779-766-8
Softcover ISBN
978-1-4939-6206-8
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XI, 440
Number of Illustrations
62 b/w illustrations, 8 illustrations in colour
Topics