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  • © 2012

Pain Research

Methods and Protocols

Editors:

  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts

Part of the book series: Methods in Molecular Biology (MIMB, volume 851)

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Table of contents (21 protocols)

  1. Front Matter

    Pages i-xi
  2. Advancements in Pain Research

    • Z. David Luo
    Pages 1-8
  3. Genomic Methods for Clinical and Translational Pain Research

    • Dan Wang, Hyungsuk Kim, Xiao-Min Wang, Raymond Dionne
    Pages 9-46
  4. An Experimental Model of Headache-Related Pain

    • Rebecca M. Edelmayer, Michael H. Ossipov, Frank Porreca
    Pages 109-120
  5. A Rodent Model of Trigeminal Neuralgia

    • David C. Yeomans, Mikhail Klukinov
    Pages 121-131
  6. New Models of Experimental Parotitis and Parotid Gland Distension in Rats

    • Akiko Okada-Ogawa, Masamichi Shinoda, Kuniya Honda, Koichi Iwata
    Pages 133-148
  7. A Rat Pain Model of Facial Cancer

    • Kentaro Ono, Nozomu Harano, Kiyotoshi Inenaga, Osamu Nakanishi
    Pages 149-157
  8. Orofacial Pain Models and Behavior Assessment

    • Timothy K. Y. Kaan, Peter T. Ohara, Luc Jasmin
    Pages 159-170
  9. Unilateral T13 and L1 Dorsal Root Avulsion: Methods for a Novel Model of Central Neuropathic Pain

    • Julie Wieseler, Amanda Ellis, Steven F. Maier, Linda R. Watkins, Scott Falci
    Pages 171-183
  10. A Rat Chronic Pain Model of Spinal Cord Contusion Injury

    • Kelli Sharp, Amin Boroujerdi, Oswald Steward, Z. David Luo
    Pages 195-203
  11. The Spared Nerve Injury Model of Neuropathic Pain

    • Marie Pertin, Romain-Daniel Gosselin, Isabelle Decosterd
    Pages 205-212
  12. Rat Models of Pancreatitis Pain

    • Karin N. Westlund, Louis Vera-Portocarrero
    Pages 223-238
  13. The Monosodium Iodoacetate Model of Osteoarthritis Pain in the Rat

    • Cheryl L. Marker, James D. Pomonis
    Pages 239-248
  14. K/BxN Serum Transfer Arthritis as a Model of Inflammatory Joint Pain

    • Christina A. Christianson, Maripat Corr, Tony L. Yaksh, Camilla I. Svensson
    Pages 249-260

About this book

The advancements of medical technology, improvements in medical care, and increased patients’ life span make pain research and related drug development high priorities for both the research community and pharmaceutical companies. Rapid development of basic science research tools, such as techniques of flurometric labeling, genomic and proteomic high throughput screening, and genetically modified animals, promotes the swift acceleration of pain research to a stage allowing integrated investigations of pain processing mechanisms at the single cell and/or molecule level, and in a spatially and temporally controlled manner.  Using multidisciplinary approaches, we can dissect the complicity of the sensory circuits connecting peripheral stimulation to maladaptive changes in the sensory pathways as well as pain perceptions at the central nervous system. Pain Research: Methods and Protocols, Second Edition provides advanced techniques and animal models that are critical for integrated pain research. Written in the highly successful Methods in Molecular Biology™ series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.

 

Authoritative and accessible, Pain Research: Methods and Protocols, Second Edition serves as an ideal guide to novice pain researchers who may not have extensive experiences in the field, or to experienced pain researchers who would like to expand their research in new directions and/or to new mechanisms in different models. 

Reviews

From the reviews of the second edition:

“This second edition of Pain Research – Methods and Protocols is an excellent compendium of chapters outlining the most current techniques used to study the neurobiology of pain. … Pain Research – Methods and Protocols is aimed not only at the novice researcher with little experience in the field but also at bringing new techniques and approaches to the pain research community as a whole. The clear organizational structure of the text makes this a highly achievable goal.” (Bradley Kerr, Canadian Journal of Anesthesia/Journal Canadien d'anesthésie, Vol. 60, January, 2013)

Editors and Affiliations

  • Irvine Medical Center, Dept. Anesthesiology & Pharmacology, University of California, Orange, USA

    Z. David Luo

Bibliographic Information

  • Book Title: Pain Research

  • Book Subtitle: Methods and Protocols

  • Editors: Z. David Luo

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-61779-561-9

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media, LLC 2012

  • Hardcover ISBN: 978-1-61779-560-2Published: 16 February 2012

  • Softcover ISBN: 978-1-4939-6095-8Published: 23 August 2016

  • eBook ISBN: 978-1-61779-561-9Published: 16 February 2012

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 2

  • Number of Pages: XI, 287

  • Number of Illustrations: 63 b/w illustrations, 3 illustrations in colour

  • Topics: Molecular Medicine, Pain Medicine

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 159.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access