Skip to main content
  • Book
  • © 2012

Psychiatric Disorders

Methods and Protocols

  • Provides researchers and clinicians with clear methodologies for conducting translational bench-to-bedside studies through these detailed animal models
  • Features practical and easy-to-use protocols that are ready for the lab
  • Includes expert tips and concrete implementation advice to ensure successful results
  • Includes supplementary material: sn.pub/extras

Part of the book series: Methods in Molecular Biology (MIMB, volume 829)

Buy it now

Buying options

eBook USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

This is a preview of subscription content, log in via an institution to check for access.

Table of contents (38 protocols)

  1. Front Matter

    Pages i-xxi
  2. Overview of the Animal Research in Psychiatric Illness and Substance Abuse

    1. Front Matter

      Pages 1-1
    2. New Frontiers in Animal Research of Psychiatric Illness

      • Arie Kaffman, John J. Krystal
      Pages 3-30
    3. Qualitative Versus Quantitative Methods in Psychiatric Research

      • Mahdi Razafsha, Hura Behforuzi, Hassan Azari, Zhiqun Zhang, Kevin K. Wang, Firas H. Kobeissy et al.
      Pages 49-62
  3. Methods in Animal Models of Psychiatric Illness

    1. Front Matter

      Pages 63-63
    2. Rodent Models of Adaptive Decision Making

      • Alicia Izquierdo, Annabelle M. Belcher
      Pages 85-101
    3. Animal Models of Depression and Neuroplasticity: Assessing Drug Action in Relation to Behavior and Neurogenesis

      • Ying Xu, Philip A. Barish, Jianchun Pan, William O. Ogle, James M. O’Donnell
      Pages 103-124
    4. Modeling Depression in Animal Models

      • David H. Overstreet
      Pages 125-144
    5. Behavioral Model for Assessing Cognitive Decline

      • Michael Guidi, Thomas C. Foster
      Pages 145-153
    6. The Pemoline Model of Self-Injurious Behaviour

      • Darragh P. Devine
      Pages 155-163
    7. Modeling Risky Decision Making in Rodents

      • Nicholas W. Simon, Barry Setlow
      Pages 165-175
    8. An Animal Model to Study the Molecular Basis of Tardive Dyskinesia

      • Mahendra Bishnoi, Ravneet K. Boparai
      Pages 193-201
  4. Methods in Animal Models of Substance Abuse

    1. Front Matter

      Pages 203-203
    2. Models of Chronic Alcohol Exposure and Dependence

      • Darin J. Knapp, George R. Breese
      Pages 205-230
    3. Rat Models of Prenatal and Adolescent Cannabis Exposure

      • Jennifer A. DiNieri, Yasmin L. Hurd
      Pages 231-242
    4. Modeling Nicotine Addiction in Rats

      • Stephanie Caille, Kelly Clemens, Luis Stinus, Martine Cador
      Pages 243-256

About this book

New high throughput techniques in neuroscience and psychiatry have enhanced the development of experimental, customizable animal models that are predictive of human neuropsychiatric pathology and give vital insights on the mechanisms and pathways involved. In Psychiatric Disorders: Methods and Protocols, key experts have written integrated chapters on neuropsychiatric research sharing their insightful expertise and opinions focusing on both the animal models as well as the cutting edge techniques applied. Beginning with an overview of the animal research in psychiatric illness and substance abuse, this comprehensive volume continues with the modeling of neuropsychiatric illness, drug abuse paradigms and techniques, biomarker identification, autoimmune inflammatory response, and neuroendocrine alteration in the areas of psychiatry, as well as state-of-the-art “Omics approaches” and neurosystems biology/data mining techniques to compute and analyze genomic and proteomics alteration occurring within neuropsychiatric models.  As a part of the highly successful Methods in Molecular Biology™ series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

 

Thorough and easily applicable, Psychiatric Disorders: Methods and Protocols offers the detailed and clearly illustrated tools necessary for neuroscientists and psychiatrists to handle many unanswered scientific questions with a more creative and insightful approach.

Reviews

From the reviews:

“This is a comprehensive compilation of in vivo and in vitro neuropsychiatric research methods and protocols on animal models and cutting-edge techniques in the wide spectrum of psychiatric illnesses. … It is written for graduates, postdoctoral workers, and established scientists working on behavioral and molecular neuropsychiatric research. … The detailed methods and protocols make this a quality book for any researcher in the field of neuroscience and psychiatry.” (Valerie E. Mathis-Allen, Doody’s Book Reviews, May, 2012)

Editors and Affiliations

  • McKnight Brain Institute, Department of Psychiatry, University of Florida, Gainesville, USA

    Firas H. Kobeissy

Bibliographic Information

  • Book Title: Psychiatric Disorders

  • Book Subtitle: Methods and Protocols

  • Editors: Firas H. Kobeissy

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-61779-458-2

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media, LLC 2012

  • Hardcover ISBN: 978-1-61779-457-5Published: 10 January 2012

  • Softcover ISBN: 978-1-4939-5865-8Published: 23 August 2016

  • eBook ISBN: 978-1-61779-458-2Published: 11 January 2012

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: XXI, 615

  • Topics: Neurosciences, Psychiatry, Animal Models

Buy it now

Buying options

eBook USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access