Methods in Molecular Biology

mTOR

Methods and Protocols

Editors: Weichhart, Thomas (Ed.)

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  • Unites current biochemical assays and in vitro as well as in vivo models
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
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eBook $139.00
price for USA in USD
  • ISBN 978-1-61779-430-8
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
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Hardcover $219.99
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Softcover $179.99
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About this book

Since its discovery, the mammalian target of rapamycin (mTOR) has been shown to regulate many critical molecular processes in eukaryotes such as metabolism, growth, survival, aging, synaptic plasticity, memory, and immunity. In mTOR: Methods and Protocols expert researchers in the field detail many of the methods which are now commonly used to study mTOR. These include methods and techniques  used for the study of the mTOR pathway and potential therapeutic applications of mTOR inhibitors  such as, immunosuppressive and anticancer agents. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.

 

Authoritative and practical, mTOR: Methods and Protocols seeks to aid scientists in the further study of this crucially important molecule  ranging from the analysis of signal transduction events within a cell to the assessment of complex human diseases such as metabolic disorders or cancer.

Table of contents (29 chapters)

Table of contents (29 chapters)
  • Mammalian Target of Rapamycin: A Signaling Kinase for Every Aspect of Cellular Life

    Pages 1-14

    Weichhart, Thomas

  • Biochemical and Pharmacological Inhibition of mTOR by Rapamycin and an ATP-Competitive mTOR Inhibitor

    Pages 15-28

    Yu, Ker (et al.)

  • Evaluation of the Nutrient-Sensing mTOR Pathway

    Pages 29-44

    Hong, Sungki (et al.)

  • mTOR Activity Under Hypoxia

    Pages 45-58

    Vadysirisack, Douangsone D. (et al.)

  • Isolation of the mTOR Complexes by Affinity Purification

    Pages 59-74

    Sarbassov, Dos D. (et al.)

Buy this book

eBook $139.00
price for USA in USD
  • ISBN 978-1-61779-430-8
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • Immediate eBook download after purchase and usable on all devices
  • Bulk discounts available
Hardcover $219.99
price for USA in USD
Softcover $179.99
price for USA in USD
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Bibliographic Information

Bibliographic Information
Book Title
mTOR
Book Subtitle
Methods and Protocols
Editors
  • Thomas Weichhart
Series Title
Methods in Molecular Biology
Series Volume
821
Copyright
2012
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-61779-430-8
DOI
10.1007/978-1-61779-430-8
Hardcover ISBN
978-1-61779-429-2
Softcover ISBN
978-1-4939-6209-9
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XIII, 444
Topics