Methods in Molecular Biology

Adeno-Associated Virus

Methods and Protocols

Editors: Snyder, Richard O., Moullier, Philippe (Eds.)

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  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
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eBook $119.00
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  • ISBN 978-1-61779-370-7
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About this book

Today, progress in rAAV-mediated gene transfer is so robust that long-term, efficient, and regulatable transgene expression is reproducibly achieved in large animal models. The complexity of  gene transfer agents in the context of their clinical use requires investigators from a wide variety of backgrounds to have an understanding — or at least an appreciation of — the regulatory environment and constraints that affect vector design, manufacturing, pre-clinical testing, and clinical use, with an emphasis on patient protection. In Adeno-Associated Virus: Methods and Protocols, experts from the United States and Europe have contributed current knowledge of this multi-dimensional field relating to the biology of AAV, rAAV vector design, vector manufacturing and product testing, performance of rAAV vectors in major organs, rAAV-related immunological issues, design of animal and clinical studies, and clinical experience. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.

 

Authoritative and accessible, Adeno-Associated Virus: Methods and Protocols provides a complete and comprehensive understanding of this multi-disciplinary and rapidly progressing field.

Table of contents (18 chapters)

Table of contents (18 chapters)

Buy this book

eBook $119.00
price for USA in USD
  • ISBN 978-1-61779-370-7
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • Immediate eBook download after purchase and usable on all devices
  • Bulk discounts available
Hardcover $219.99
price for USA in USD
Softcover $159.99
price for USA in USD
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Bibliographic Information

Bibliographic Information
Book Title
Adeno-Associated Virus
Book Subtitle
Methods and Protocols
Editors
  • Richard O. Snyder
  • Philippe Moullier
Series Title
Methods in Molecular Biology
Series Volume
807
Copyright
2011
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-61779-370-7
DOI
10.1007/978-1-61779-370-7
Hardcover ISBN
978-1-61779-369-1
Softcover ISBN
978-1-4939-6175-7
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XIII, 462
Number of Illustrations
23 b/w illustrations, 20 illustrations in colour
Topics