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Methods in Molecular Biology

Yeast Systems Biology

Methods and Protocols

Editors: Castrillo, Juan I., Oliver, Stephen G. (Eds.)

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  • Presents an up-to-date view of yeast as a model eukaryote for systems biology studies
  • Provides practical, easy to use methodologies
  • Includes key tips and vital implementation advice from the experts
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eBook $149.00
price for USA in USD
  • ISBN 978-1-61779-173-4
  • Digitally watermarked, DRM-free
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  • Immediate eBook download after purchase
Hardcover $199.00
price for USA in USD
Softcover $199.00
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About this book

Systems Biology aims at deciphering the genotype-phenotype relationships at the levels of genes, transcripts (RNAs), peptides, proteins, metabolites, and environmental factors participating in complex cellular networks in order to reveal the mechanisms and principles governing the behavior of complex biological systems.  Yeast Systems Biology: Methods and Protocols presents an up-to-date view of the optimal characteristics of the yeast Saccharomyces cerevisiae as a model eukaryote, perspective on the latest experimental and computational techniques  for systems biology studies, most of which were first designed for and validated in yeast, and selected examples of yeast systems biology studies and their applications in biotechnology and medicine.  These experiments under controlled conditions can uncover the complexity and interplay of biological networks with their dynamics, basic principles of internal organization, and balanced orchestrated functions between organelles in direct interaction with the environment as well as the characterization of short and long-term effects of perturbations and dysregulation of networks that may illuminate the origin of complex human diseases.  Written for the highly successful Methods in Molecular Biology™ series, this volume contains the kind of detailed description and implementation advice that is crucial for getting optimal results.

 

Practical and cutting-edge, Yeast Systems Biology: Methods and Protocols serves researchers interested in comprehensive systems biology strategies in well-defined model systems with specific objectives as well as a better knowledge of the latest post-genomic strategies at all ‘omic levels and computational approaches towards analysis, integration, and modeling of biological systems, from single-celled organisms to higher eukaryotes.

Table of contents (28 chapters)

Table of contents (28 chapters)
  • Yeast Systems Biology: The Challenge of Eukaryotic Complexity

    Pages 3-28

    Castrillo, Juan I. (et al.)

  • Saccharomyces cerevisiae: Gene Annotation and Genome Variability, State of the Art Through Comparative Genomics

    Pages 31-40

    Louis, Ed

  • Genome-Wide Measurement of Histone H3 Replacement Dynamics in Yeast

    Pages 41-60

    Rando, Oliver J.

  • Genome-Wide Approaches to Studying Yeast Chromatin Modifications

    Pages 61-71

    Schones, Dustin E. (et al.)

  • Absolute and Relative Quantification of mRNA Expression (Transcript Analysis)

    Pages 73-86

    Hayes, Andrew (et al.)

Buy this book

eBook $149.00
price for USA in USD
  • ISBN 978-1-61779-173-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.00
price for USA in USD
Softcover $199.00
price for USA in USD
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Bibliographic Information

Bibliographic Information
Book Title
Yeast Systems Biology
Book Subtitle
Methods and Protocols
Editors
  • Juan I. Castrillo
  • Stephen G. Oliver
Series Title
Methods in Molecular Biology
Series Volume
759
Copyright
2011
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-61779-173-4
DOI
10.1007/978-1-61779-173-4
Hardcover ISBN
978-1-61779-172-7
Softcover ISBN
978-1-4939-6135-1
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XIV, 535
Number of Illustrations
83 b/w illustrations, 2 illustrations in colour
Topics