Overview
- Presents an up-to-date view of yeast as a model eukaryote for systems biology studies
- Provides practical, easy to use methodologies
- Includes key tips and vital implementation advice from the experts
- Includes supplementary material: sn.pub/extras
Part of the book series: Methods in Molecular Biology (MIMB, volume 759)
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Table of contents (28 protocols)
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Yeast Systems Biology
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Experimental Systems Biology: High-Throughput Genome-Wide And Molecular Studies
Keywords
- Biological networks
- Biotechnology
- Budding yeast
- Computational systems biology
- Eukaryotic systems
- Experimental 'omics techniques
- Experimental systems biology
- High-throughput genome-wide studies
- Medicine
- Model eukaryote
- Modeling
- Network Biology
- Next Generation Sequencing (NGS)
- Saccharomyces cerevisiae
- gene expression
About this book
Systems Biology aims at deciphering the genotype-phenotype relationships at the levels of genes, transcripts (RNAs), peptides, proteins, metabolites, and environmental factors participating in complex cellular networks in order to reveal the mechanisms and principles governing the behavior of complex biological systems. Yeast Systems Biology: Methods and Protocols presents an up-to-date view of the optimal characteristics of the yeast Saccharomyces cerevisiae as a model eukaryote, perspective on the latest experimental and computational techniques for systems biology studies, most of which were first designed for and validated in yeast, and selected examples of yeast systems biology studies and their applications in biotechnology and medicine. These experiments under controlled conditions can uncover the complexity and interplay of biological networks with their dynamics, basic principles of internal organization, and balanced orchestrated functions between organelles in direct interaction with the environment as well as the characterization of short and long-term effects of perturbations and dysregulation of networks that may illuminate the origin of complex human diseases. Written for the highly successful Methods in Molecular Biology™ series, this volume contains the kind of detailed description and implementation advice that is crucial for getting optimal results.
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Practical and cutting-edge, Yeast Systems Biology: Methods and Protocols serves researchers interested in comprehensive systems biology strategies in well-defined model systems with specific objectives as well as a better knowledge of the latest post-genomic strategies at all ‘omic levels and computational approaches towards analysis, integration, and modeling of biological systems, from single-celled organisms to higher eukaryotes.Editors and Affiliations
Bibliographic Information
Book Title: Yeast Systems Biology
Book Subtitle: Methods and Protocols
Editors: Juan I. Castrillo, Stephen G. Oliver
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-61779-173-4
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC 2011
Hardcover ISBN: 978-1-61779-172-7Published: 23 August 2011
Softcover ISBN: 978-1-4939-6135-1Published: 23 August 2016
eBook ISBN: 978-1-61779-173-4Published: 23 August 2011
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XIV, 535
Number of Illustrations: 83 b/w illustrations, 2 illustrations in colour
Topics: Microbiology, Gene Expression