Methods in Molecular Biology

Signal Transduction Protocols

Editors: Luttrell, Louis M., Ferguson, Stephen S. G. (Eds.)

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  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
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  • ISBN 978-1-61779-160-4
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Hardcover $219.99
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About this book

It is increasingly clear that signal transduction is a highly organized and integrated process.  Divided into two convenient sections, Signal Transduction Protocols, Third Edition focuses on experimental approaches to better understand the complexity of signal transduction.  Introductory chapters provide perspective on several of the challenges involved in signal transduction research and offer guidance on selecting the best approaches to various types of questions.  The individual chapters provide detailed experimental protocols covering various topics, from the effects of ligand binding on receptor conformation and effector coupling, to moving inside the cell in order to capture the spatial and temporal characteristics of signaling events. Written in the highly successful Methods in Molecular Biology™ series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.

 

Authoritative and accessible, Signal Transduction Protocols serves as an ideal guide to scientists of all backgrounds and is a valuable resource for future progress in the field of signal transduction research.

Reviews

From the reviews of the third edition:

“This well-illustrated book on signal transduction protocols is a valuable resource for scientists interested in learning the intricate details of complex signaling events that take place within the cell … . Although written for the scientists in the field of signal transduction research, it also will be useful for graduate students and other investigators in pharmacology interested in this area. … Given the rapid advances in the field of signal transduction, this third edition is essential.” (Omer Iqbal, Doody’s Book Reviews, March, 2012)

Table of contents (25 chapters)

Table of contents (25 chapters)
  • Refining Efficacy: Allosterism and Bias in G Protein-Coupled Receptor Signaling

    Luttrell, Louis M. (et al.)

    Pages 3-35

  • Imaging-Based Approaches to Understanding G Protein-Coupled Receptor Signalling Complexes

    Pétrin, Darlaine (et al.)

    Pages 37-60

  • Improving Drug Discovery with Contextual Assays and Cellular Systems Analysis

    Westwick, John K. (et al.)

    Pages 61-73

  • RGS-Insensitive Gα Subunits: Probes of Gα Subtype-Selective Signaling and Physiological Functions of RGS Proteins

    Kaur, Kuljeet (et al.)

    Pages 75-98

  • Bioinformatic Approaches to Metabolic Pathways Analysis

    Maudsley, Stuart (et al.)

    Pages 99-130

Buy this book

eBook $139.00
price for USA in USD (gross)
  • ISBN 978-1-61779-160-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.99
price for USA in USD
  • ISBN 978-1-61779-159-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $179.00
price for USA in USD
  • ISBN 978-1-4939-6108-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Signal Transduction Protocols
Editors
  • Louis M. Luttrell
  • Stephen S. G. Ferguson
Series Title
Methods in Molecular Biology
Series Volume
756
Copyright
2011
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-61779-160-4
DOI
10.1007/978-1-61779-160-4
Hardcover ISBN
978-1-61779-159-8
Softcover ISBN
978-1-4939-6108-5
Series ISSN
1064-3745
Edition Number
3
Number of Pages
XIV, 430
Topics