Happy holidays from us to you—get up to $30 off your next print or eBook! Shop now >>

Methods in Molecular Biology

The Blood-Brain and Other Neural Barriers

Reviews and Protocols

Editors: Nag, Sukriti (Ed.)

  • Reviews the relevant aspects of brain biology then delves into in-depth, practical laboratory protocols Explores beyond the blood-brain barrier into other vital neural barriers Features tips for completing the protocols successfully, relayed by the expert contributors from their wealth of experience

Buy this book

eBook $149.00
price for USA in USD (gross)
  • ISBN 978-1-60761-938-3
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.00
price for USA in USD
  • ISBN 978-1-60761-937-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $199.00
price for USA in USD
  • ISBN 978-1-4939-6144-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Evolving technologies starting with tracer studies, and more recently with genomics and proteomics, have provided novel information about the molecular properties of cerebral endothelium and astrocytes; however, further studies must be done in animal models of neurological diseases and in humans to get a clearer understanding of the pathogenesis of blood-brain barrier (BBB) breakdown in nervous system diseases. In The Blood-Brain and Other Neural Barriers: Reviews and Protocols, experts in the field present a series of cutting-edge protocols which can be used to study the barriers. Opening with detailed information on components of the neurovascular unit as well as the blood-cerebrospinal, blood-retinal, and blood-nerve barriers, the book continues with meticulous techniques to image the barriers in humans and experimental animals, followed by cutting-edge molecular techniques to study the BBB and novel models to study the barriers, and it concludes with techniques for the delivery of therapeutic agents across the BBB. Written in the highly successful Methods in Molecular Biology™ series format, protocol chapters include introductions to their respective topics, lists of the necessary materials, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, The Blood-Brain and Other Neural Barriers: Reviews and Protocols will aid the research efforts of not only graduate students but also more experienced investigators and support future studies of these vital systems.

Table of contents (25 chapters)

  • Morphology and Properties of Brain Endothelial Cells

    Nag, Sukriti

    Pages 3-47

  • Morphology and Properties of Pericytes

    Dore-Duffy, Paula (et al.)

    Pages 49-68

  • Morphology and Properties of Astrocytes

    Nag, Sukriti

    Pages 69-100

  • The Blood–Cerebrospinal Fluid Barrier: Structure and Functional Significance

    Johanson, Conrad E. (et al.)

    Pages 101-131

  • The Blood-Retinal Barrier: Structure and Functional Significance

    Runkle, E. Aaron (et al.)

    Pages 133-148

Buy this book

eBook $149.00
price for USA in USD (gross)
  • ISBN 978-1-60761-938-3
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.00
price for USA in USD
  • ISBN 978-1-60761-937-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $199.00
price for USA in USD
  • ISBN 978-1-4939-6144-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
The Blood-Brain and Other Neural Barriers
Book Subtitle
Reviews and Protocols
Editors
  • Sukriti Nag
Series Title
Methods in Molecular Biology
Series Volume
686
Copyright
2011
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-60761-938-3
DOI
10.1007/978-1-60761-938-3
Hardcover ISBN
978-1-60761-937-6
Softcover ISBN
978-1-4939-6144-3
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XIV, 502
Topics