Methods in Molecular Biology

Anticoagulants, Antiplatelets, and Thrombolytics

Editors: MOUSA, SHAKER (Ed.)

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  • Fully updates the popular original edition with cutting-edge approaches
  • Provides easy-to-use, readily reproducible protocols
  • Includes expert tips on troubleshooting and avoiding common pitfalls
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About this book

During the past decade, remarkable progress has been made in the development of newer drugs to prevent and treat thromboembolic disorders, such as oral direct anti-Xa and anti-IIa antagonists, as well as oral antiplatelet ADP antagonists with rapid onset and offset. In addition, there has been concentrated effort aimed at identifying novel uses of traditional antithrombotic drugs, such as aspirin, heparin, and oral anticoagulants, as well as combinations of agents, such as more than one antiplatelet, antiplatelet with anticoagulant, antiplatelet with or without thrombolytic. Anticoagulants, Antiplatelets, and Thrombolytics, Second Edition provides updates on various strategies in thrombosis, experimental models, and clinical and recent advances in the discovery and development of novel antithrombotics. As a volume in the highly successful Methods in Molecular Biology™ series, this collection provides the kind of detailed description and implementation advice that is crucial for getting optimal results. Easy to use and up to date, Anticoagulants, Antiplatelets, and Thrombolytics, Second Edition is an ideal guide for researchers aiming for the future of this vital field, focusing on the prevention of thromboembolic disorders and the protection of the vascular endothelium.

Reviews

From the reviews of the second edition:

“Text thoroughly presented the subject of antithrombotic and anticoagulant therapy in great depth and with complete review of the subject. In 13 chapters outstanding experts in their field have provided the cardiovascular specialist, hematologist, and pathologist with a thorough updating of the pharmacology of antithrombotic and anticoagulant therapy. … text should provide anyone working in the field of cardiovascular medicine or surgery and in hematology or pathology with a way to keep current with developments in the field of cardiovascular pharmacology. We recommend it highly.” (Harry L. Messmore and William H. Wehrmacher, Clinical and Applied Thrombosis/Hemostasis, November, 2010)

“Recent advances in testing and use of anticoagulants, antiplatelets, and thrombolytics and the essentials of efficacy testing, novel direct thrombin inhibitors, use of naturally-derived products, and pharmacogenomics in thrombosis. … The book is likely to be of interest to both academic scientists and practitioners interested in the treatment of patients with thrombosis. … This is very likely to make it onto the shelf in our laboratory, in particular as a reference for current advances in antithrombotics and thrombolytics.” (James P. Luyendyk, Doody’s Review Service, December, 2010)


Table of contents (13 chapters)

Table of contents (13 chapters)
  • In Vitro Methods of Evaluating Antithrombotics and Thrombolytics

    Pages 1-28

    Mousa, Shaker A.

  • In Vivo Models for the Evaluation of Antithrombotics and Thrombolytics

    Pages 29-107

    Mousa, Shaker A.

  • Heparin and Low-Molecular Weight Heparins in Thrombosis and Beyond

    Pages 109-132

    Mousa, Shaker A.

  • Laboratory Methods and Management of Patients with Heparin-Induced Thrombocytopenia

    Pages 133-156

    Prechel, Margaret (et al.)

  • Novel Anticoagulant Therapy: Principle and Practice

    Pages 157-179

    Mousa, Shaker A.

Buy this book

eBook $139.00
price for USA in USD
  • ISBN 978-1-60761-803-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • Immediate eBook download after purchase and usable on all devices
  • Bulk discounts available
Hardcover $179.99
price for USA in USD
Softcover $179.99
price for USA in USD
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Bibliographic Information

Bibliographic Information
Book Title
Anticoagulants, Antiplatelets, and Thrombolytics
Editors
  • SHAKER MOUSA
Series Title
Methods in Molecular Biology
Series Volume
663
Copyright
2010
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-60761-803-4
DOI
10.1007/978-1-60761-803-4
Hardcover ISBN
978-1-60761-802-7
Softcover ISBN
978-1-4939-6097-2
Series ISSN
1064-3745
Edition Number
2
Number of Pages
XI, 316
Topics