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Methods in Molecular Biology

Cardiovascular Genomics

Methods and Protocols

Editors: DiPetrillo, Keith (Ed.)

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  • Covers a range of phenotyping, bioinformatics, and statistical methods required for cardiovascular genomic research
  • Provides detailed protocols for evaluating important cardiovascular diseases in rodents
  • Highlights expert insights to avoid or overcome technical difficulties of phenotyping rodent models
  • Includes methods for integrating genotype, gene expression, and phenotype data from rodents and humans
  • Provides bioinformatics and statistical methods applicable to genomic research into many varied diseases
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eBook $109.00
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  • ISBN 978-1-60761-247-6
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Hardcover $219.99
price for USA in USD
  • ISBN 978-1-60761-246-9
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  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
Softcover $149.00
price for USA in USD
  • ISBN 978-1-61779-643-2
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  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
About this book

As two of the leading causes of death worldwide, heart disease and stroke represent a clear target for genomic research aimed at deciphering the genes and cellular pathways that underlie cardiovascular disease and creating improved therapies. In Cardiovascular Genomics: Methods and Protocols, experts in the field provide methods for cardiovascular phenotyping of rodent models in the first section of the volume and for statistical and bioinformatic integration of phenotype data with genome-wide genotype and expression data in the second section. Understanding these diverse methods will allow an individual laboratory to utilize these genomic methods independently or to better prepare for collaboration with scientists having expertise in other disciplines in order to uncover genes affecting cardiovascular disease. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary equipment, materials, and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.

Cutting-edge and easy-to-use, Cardiovascular Genomics: Methods and Protocols will enable researchers to identify causal genes and novel molecular targets that can lead to vital new treatments for cardiovascular disease.

Reviews

From the reviews: “The book appears to provide a practical guide on a number of laboratory-based molecular methods that are likely to be useful in carrying out human and animal experiments to generate data and information for … complex cardiovascular conditions. … Although this book is well produced with excellent layout, it will probably find a … place on any researcher’s book shelf. … laboratories may consider keeping a copy in the library for quick reference and useful in teaching and training of young investigators in molecular genomics.” (Dhavendra Kumar, Human Genetics, Vol. 127, 2010)

Table of contents (18 chapters)

Table of contents (18 chapters)
  • Modes of Defining Atherosclerosis in Mouse Models: Relative Merits and Evolving Standards

    Pages 1-15

    Daugherty, Alan (et al.)

  • Evaluating Micro- and Macro-vascular Disease, the End Stage of Atherosclerosis, in Rat Models

    Pages 17-44

    Russell, James C.

  • Non-invasive Blood Pressure Measurement in Mice

    Pages 45-55

    Feng, Minjie (et al.)

  • Direct Blood Pressure Monitoring in Laboratory Rodents via Implantable Radio Telemetry

    Pages 57-73

    Huetteman, Daniel A. (et al.)

  • Measuring Kidney Function in Conscious Mice

    Pages 75-94

    Mattson, David L.

Buy this book

eBook $109.00
price for USA in USD
  • ISBN 978-1-60761-247-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.99
price for USA in USD
  • ISBN 978-1-60761-246-9
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
Softcover $149.00
price for USA in USD
  • ISBN 978-1-61779-643-2
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
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Bibliographic Information

Bibliographic Information
Book Title
Cardiovascular Genomics
Book Subtitle
Methods and Protocols
Editors
  • Keith DiPetrillo
Series Title
Methods in Molecular Biology
Series Volume
573
Copyright
2009
Publisher
Humana Press
Copyright Holder
Humana Press
eBook ISBN
978-1-60761-247-6
DOI
10.1007/978-1-60761-247-6
Hardcover ISBN
978-1-60761-246-9
Softcover ISBN
978-1-61779-643-2
Series ISSN
1064-3745
Edition Number
1
Number of Pages
X, 350
Number of Illustrations
84 b/w illustrations
Topics