Methods in Molecular Biology

Analgesia

Methods and Protocols

Editors: Szallasi, Arpad (Ed.)

  • Presents a framework of basic and clinical studies aimed at developing improved analgesic drugs
  • Contains detailed protocols for studying both ion channels and G protein-linked receptors as targets for analgesics
  • Delves into subjects as diverse as alternatives to animal pain models (e.g. C. elegans and Drosophila), photoaffinity labeling of volatile analgesic drugs, standardization of pain measurements in clinical trials, congenital insensitivity to pain, and personalized medicine
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eBook $169.00
price for USA in USD (gross)
  • ISBN 978-1-60327-323-7
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.99
price for USA in USD
  • ISBN 978-1-60327-322-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $219.99
price for USA in USD
  • ISBN 978-1-4939-5699-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Chronic pain is a complex phenomenon, which continues to remain undertreated in the majority of affected patients thus representing a significant unmet medical need, but the development of cellular, subcellular, and molecular methods of approaching this epidemic of pain shows great promise. In Analgesia: Methods and Protocols, experts in the field present thorough coverage of molecular analgesia research methods from target discovery through target validation and clinical testing to tolerance and dependence, with extensive chapters on emerging receptor classes as targets for analgesic drugs and innovative analgesic strategies. As a volume in the highly successful Methods in Molecular Biology™ series, the chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes sections with tips on troubleshooting and avoiding known pitfalls.

Comprehensive and essential, Analgesia: Methods and Protocols promises to aid and enrich the research of all those scientists and clinicians who are interested in what the increasingly molecular future has in store for analgesia research, from the molecular research bench through the animal laboratory to the bedside.

Reviews

From the reviews:

“The text provides all one wishes to know about research methods in analgesia. … editor’s decision to invite groups of authors and experts from the different areas of research in analgesia, has allowed a broad and up-to-date view of the field. … This book is of great value for investigators, students and physicians interested in understanding pain and the mechanisms involved in its relief. On consulting this book, researchers, students and professionals will have the opportunity to update their knowledge of experimental methods in analgesia.” (Zuleica Bruno Fortes, Brazilian Journal of Pharmaceutical Sciences, Vol. 46 (4), October-December, 2010)

“This book is a collection of methods used to study pain physiology, pharmacology, and genetics described by researchers in the field. … intended to assist basic scientists and clinicians who are interested in the molecular aspects of pain research. … This is a most unique book in the field of pain medicine. … The book imparts a lot of information about the future of pain medicine and is a must read for pain physicians who want to be at their best when managing their patients.” (Tariq M. Malik, Doody’s Book Reviews, August, 2010)

Table of contents (39 chapters)

  • Alternatives to Mammalian Pain Models 1: Use of C. elegans for the Study of Volatile Anesthetics

    Steele, Louise M. (et al.)

    Pages 1-17

  • Alternatives to Mammalian Pain Models 2: Using Drosophila to Identify Novel Genes Involved in Nociception

    Caldwell, Jason C. (et al.)

    Pages 19-29

  • Animal Models of Acute Surgical Pain

    Kim, Hyangin (et al.)

    Pages 31-39

  • Animal Models of Acute and Chronic Inflammatory and Nociceptive Pain

    Boyce-Rustay, Janel M. (et al.)

    Pages 41-55

  • Noxious Heat Threshold Measured with Slowly Increasing Temperatures: Novel Rat Thermal Hyperalgesia Models

    Bölcskei, Kata (et al.)

    Pages 57-66

Buy this book

eBook $169.00
price for USA in USD (gross)
  • ISBN 978-1-60327-323-7
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.99
price for USA in USD
  • ISBN 978-1-60327-322-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $219.99
price for USA in USD
  • ISBN 978-1-4939-5699-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Analgesia
Book Subtitle
Methods and Protocols
Editors
  • Arpad Szallasi
Series Title
Methods in Molecular Biology
Series Volume
617
Copyright
2010
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-60327-323-7
DOI
10.1007/978-1-60327-323-7
Hardcover ISBN
978-1-60327-322-0
Softcover ISBN
978-1-4939-5699-9
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XVII, 560
Topics