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Contemporary Hematology

Stem Cell Transplantation for Hematologic Malignancies

Editors: Soiffer, Robert J. (Ed.)

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  • ISBN 978-1-59259-733-8
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About this book

Over the past several years, fundamental notions about transplantation have changed to such a degree that even the once familiar term, bone marrow transplant, is becoming increasingly outdated. In Stem Cell Transplantation for Hematologic Malignancies, leading investigators and physicians/clinicans comprehensively survey the current state-of-the-art in hematopoietic stem cell transplantation for malignant disease. The authors focus on the indications and results of transplantation for acute leukemia, chronic myelogenous leukemia, lymphoma, multiple myeloma, and breast cancer, providing insight into the relative merits of transplant and nontransplant approaches to these disorders. Special attention is given to transplant-related complications, including the pathophysiology and clinical consequences of acute and chronic graft-vs-host disease (GVHD), delayed immune reconstitution leading to infectious complications, and organ damage to the lung and liver. Additional chapters address the sources of stem cells and the effects of graft manipulation used to eliminate residual contaminating tumor cells in autologous transplantation, or to reduce the number of T lymphocytes causing GVHD in allogenic transplantation. Also discussed are the role of donor lymphocyte infusions in the treatment and prevention of relapse after stem cell transplantation and their influence on the development of nonmyeloablative transplantation.
Comprehensive and state-of-the-art, Stem Cell Transplantation for Hematologic Malignancies outlines the many exciting advances that are working toward realization today while fully explaining the process of stem cell transplantation for malignant disease.

Reviews

"Current transplant approaches to the individual hematologic malignancies are discussed and the literature critiqued. The diverse complications of transplantation are discussed in considerable detail; the authors clearly define the underlying pathophysiology as well as state-of-the-art treatment approaches. Chapters on the new field of alternative graft sources is one of the book's best features and include unrelated, haploidentical and umbilical cord transplantation. This is a high-quality publication that is easy to read and not as overwhelming as the larger, more comprehensive transplant books. It is full of helpful information and references. "-Doody's Health Sciences Book Review Journal

"This book provides a timely update and a valuable summary of this rapidly evolving field." -Annals of Internal Medicine

"...a comprehensive review of the current state of the art in hematopoietic setm-cell transplantation for hematologic cancers and breast cancer...belongs in every facility that performs hematopoietic stem-cell transplantation." - New England Journal of Medicine

Table of contents (22 chapters)

Table of contents (22 chapters)
  • Allogeneic and Autologous Stem Cell Transplantation for Acute Leukemia and Myelodysplasia in the Adult

    Pages 3-24

    Cohen, Sandra, MD (et al.)

  • Hematopoietic Stem Cell Transplantation for Chronic Myelogenous Leukemia

    Pages 25-45

    Caldera, Humberto, MD (et al.)

  • Stem Cell Transplantation for Hodgkin’s and Non-Hodgkin’s Lymphomas

    Pages 47-84

    Kenney, Thomas J., MD (et al.)

  • Autologous and Allogeneic Transplantation for Multiple Myeloma

    Pages 85-97

    Davies, Faith E., MD (et al.)

  • Hematopoietic Progenitor Cell Transplantation for Breast Cancer

    Pages 99-132

    Nieto, Yago, MD (et al.)

Buy this book

eBook $74.99
price for USA in USD (gross)
  • ISBN 978-1-59259-733-8
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
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Bibliographic Information

Bibliographic Information
Book Title
Stem Cell Transplantation for Hematologic Malignancies
Editors
  • Robert J. Soiffer
Series Title
Contemporary Hematology
Copyright
2004
Publisher
Humana Press
Copyright Holder
Humana Press
eBook ISBN
978-1-59259-733-8
DOI
10.1007/978-1-59259-733-8
Edition Number
1
Number of Pages
X, 486
Topics

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