Contemporary Cancer Research

Prostate Cancer

Biology, Genetics, and the New Therapeutics

Editors: Chung, Leland W.K. (Ed.)

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  • ISBN 978-1-59259-009-4
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About this book

Progress in sequencing and characterizing the human genome has transformed cancer genetics both conceptually and methodologically. In Prostate Cancer: Biology, Genetics, and the New Therapeutics, leading cancer biologists and clinical researchers comprehensively review the latest basic research and its translational significance for the molecular biology and genetics of prostate cancer, as well as its application in developing novel therapeutics. Highlights of recent molecular genetics research include new light on inactivated tumor suppressor genes, HPC families, the role of the androgen receptor, the progression of prostate cancer, and promising results from transcriptome profiling and proteomics. Research into the basic biology and regulatory mechanisms controlling prostate cancer growth, progression, and stromal-epithelial interaction has revealed many new possibilities for therapeutic intervention, including cell adhesion molecules, the androgen receptor, use of the nuclear matrix, Caveolin-1, and the prostate-specific membrane antigen. Among the cancer therapeutic modalities discussed are chemoprevention, radiotherapy, radical retropubic prostatectomy, the development of dendritic-cell based vaccines, differentiation therapies, and gene therapy.
Comprehensive and cutting-edge, Prostate Cancer: Biology, Genetics, and the New Therapeutics synthesizes all the major recent work that is not only rapidly unraveling the mysteries of prostate cancer, but also dramatically improving today's therapeutic approaches.

Reviews

"...the editors have done a remarkable job in selecting the topics and compiling the various articles into a comprehensive and easily accessible volume. The chapters are concise and informative, covering highly innovative studies being conducted in the field of recent years...the complexity of prostate cancer biology is well represented in the book, and the resourceful information can benefit not only those who are interested in prostate biology, but also those researchers employing molecular and cellular approaches to solve other important biological questions." - Quarterly Review of Biology

"...a welcome addition to the literature...The main strength of this book is that experts from several disciplines have contributed their thoughts on recent advances in prostate cancer...I strongly recommend this book to researchers who study prostate cancer, whether at the bench or at the bedside, and to clinicians who treat patients with prostate cancer... the book covers our current knowledge of prostate cancer and its treatment and helps define the foundation for future directions." - New England Journal of Medicine

"Well researched and extensively referenced, the book provides a valuable source of information on the current state of understanding of the molecular biology of prostate cancer, and the treatment modalities in routine clinical practice." - ACP News

"Each chapter is presented in a way that provides all available knowledge on the subject and the book structure allows readers to use a single section or chapter according to their interests. All these characteristics make the book a valuable tool to general oncologists or urologists interested in updating their basic knowledge of prostate cancer." -Annals of Oncology

Table of contents (29 chapters)

Table of contents (29 chapters)

Buy this book

eBook $74.99
price for USA in USD (gross)
  • ISBN 978-1-59259-009-4
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
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Bibliographic Information

Bibliographic Information
Book Title
Prostate Cancer
Book Subtitle
Biology, Genetics, and the New Therapeutics
Editors
  • Leland W.K. Chung
Series Title
Contemporary Cancer Research
Copyright
2001
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-59259-009-4
DOI
10.1007/978-1-59259-009-4
Edition Number
1
Number of Pages
XVIII, 531
Number of Illustrations
58 b/w illustrations, 1 illustrations in colour
Topics