Read While You Wait - Get immediate ebook access, if available*, when you order a print book

Methods in Molecular Biology

Macromolecular Drug Delivery

Methods and Protocols

Editors: Belting, Mattias (Ed.)

Free Preview
  • Provides cutting edge methods for in vitro and in vivo studies of nucleic acid-based drugs
  • Presents detailed protocols for preparation of non-viral drug delivery vehicles and artificial membrane models
  • Includes a comprehensive description of retrieval of internalizing antibodies from phage display libraries
  • Gives step-by-step methods for in vitro and in vivo studies of macromolecular delivery across biological barriers
see more benefits

Buy this book

eBook $109.00
price for USA in USD
  • ISBN 978-1-59745-429-2
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $149.99
price for USA in USD
  • ISBN 978-1-58829-999-4
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
Softcover $149.00
price for USA in USD
  • ISBN 978-1-62703-966-6
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
About this book

Macromolecular drugs hold the promise of becoming new therapeutics for several major disorders, including cancer and cardiovascular disease. This incredible potential is explored in Macromolecular Drug Delivery, a volume which gives a wide-ranging overview of contemporary methods used in the field, and which addresses the limitations presented by a lack of safe and efficient drug delivery strategies. Chapters offer information on both in vitro and in vivo methods of macromolecular delivery, thus appealing to a broad scientific audience. Composed in the highly successful Methods in Molecular Biology™ series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls.

Comprehensive and cutting-edge, Macromolecular Drug Delivery offers a platform for interdisciplinary collaboration, which should provide opportunities for new discoveries at the interface between disciplines. Ultimately, this cooperation will lead to the use of macromolecular drugs as novel diagnostic tools and, even more importantly, as a means to revolutionize the way we view and treat diseases.

Reviews

From the reviews:

"This volume … provides details and discussions on contemporary methods available to address the limitations in the delivery of these agents. … This comprehensive review will be of interest to scientists investigating either the in vitro or in vivo actions of macromolecule agents. Experts in biophysics, chemistry, cell biology, pharmaceutics, and/or preclinical and clinical dug discovery studies will find this book of value. Researchers involved in target therapy strategies for treatment of diseases will want a copy of this book." (Thomas L. Pazdernik, Doody’s Review Service, 2009)

“The title of the book will definitely attract readers of various backgrounds. It seems to indicate that the book covers the delivery of various kinds of macromolecular drugs. … This will come as a surprise for experts working with other types of macromolecular therapeutics … . the in vitro and in vivo models described in the book would be of interest to a broad scientific audience. … the book definitely contains a lot of valuable information for experimental researchers.” (Michal Pechar, ChemMedChem, Issue 4, 2009)

Table of contents (14 chapters)

Table of contents (14 chapters)
  • Developments in Macromolecular Drug Delivery

    Pages 1-10

    Belting, Mattias (et al.)

  • Synthetic vs. Natural/Biodegradable Polymers for Delivery of shRNA-Based Cancer Therapies

    Pages 11-29

    Vorhies, John S. (et al.)

  • siRNA and DNA Transfer to Cultured Cells

    Pages 31-52

    Gopalakrishnan, Bagavathi (et al.)

  • Poly(β-amino esters): Procedures for Synthesis and Gene Delivery

    Pages 53-63

    Green, Jordan J. (et al.)

  • Systemic Delivery and Pre-clinical Evaluation of Nanoparticles Containing Antisense Oligonucleotides and siRNAs

    Pages 65-83

    Zhang, Chuanbo (et al.)

Buy this book

eBook $109.00
price for USA in USD
  • ISBN 978-1-59745-429-2
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $149.99
price for USA in USD
  • ISBN 978-1-58829-999-4
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
Softcover $149.00
price for USA in USD
  • ISBN 978-1-62703-966-6
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Macromolecular Drug Delivery
Book Subtitle
Methods and Protocols
Editors
  • Mattias Belting
Series Title
Methods in Molecular Biology
Series Volume
480
Copyright
2009
Publisher
Humana Press
Copyright Holder
Humana Press
eBook ISBN
978-1-59745-429-2
DOI
10.1007/978-1-59745-429-2
Hardcover ISBN
978-1-58829-999-4
Softcover ISBN
978-1-62703-966-6
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XIV, 205
Topics

*immediately available upon purchase as print book shipments may be delayed due to the COVID-19 crisis. ebook access is temporary and does not include ownership of the ebook. Only valid for books with an ebook version. Springer Reference Works and instructor copies are not included.