Get 40% off our selection of bestselling print books in Engineering through October 31st!

Methods in Molecular Biology

Protein Structure, Stability, and Interactions

Editors: Shriver, John W. (Ed.)

  • A comprehensive guide to measuring biomolecular interactions for new as well as established investigators
  • Includes overviews of methods along with details to assist first time users
  • Covers the necessary theory for analyzing a wide array of different kinds of binding data
  • Contains descriptions of methods for studying both intermolecular and intramolecular interactions
  • Includes methods for describing interactions in vivo including the effects of solvent and crowding
see more benefits

Buy this book

eBook $139.00
price for USA in USD (gross)
  • ISBN 978-1-59745-367-7
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.00
price for USA in USD
  • ISBN 978-1-58829-954-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $179.00
price for USA in USD
  • ISBN 978-1-61737-855-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

In the areas of biochemistry and cell biology, characterizations of stability and molecular interactions call for a quantitative approach with a level of precision that matches the fine tuning of these interactions in a living cell. Supporting and up-dating previous Methods in Molecular Biology™ volumes, Protein Structure, Stability, and Interactions approaches its subject with a focus on theory and practical applications for both established methods as well as exciting new procedures. The volume presents an overview of many techniques currently used to study protein stability and interactions, including scanning and titration calorimetry, spectroscopic methods, high field NMR, and analytical ultracentrifugation. As a volume of the highly successful Methods in Molecular Biology™ series, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results.

Cutting-edge and easy to reference, Protein Structure, Stability, and Interactions is an ideal guide for all scientists interested in biomolecular interactions.

Reviews

From the reviews:

"Protein Structure, Stability, and Interactions covers a thorough list of biophysical methods as applied to proteins and their environments in vivo, in vitro, and sometimes in silico. … The book begins with a tutorial on microcalorimetry by Privalov, followed by a chapter on useful protocols for urea denaturation curves … . As a whole, this book would work as a text for an advanced course in biophysical methods or as a reference book for a biophysics laboratory." (Christopher Bystroff, Journal of the American Chemical Society, Vol. 131 (23), 2009)


Table of contents (14 chapters)

  • Microcalorimetry of Proteins and Their Complexes

    Privalov, Peter L.

    Pages 1-39

  • Determining the Conformational Stability of a Protein Using Urea Denaturation Curves

    Shaw, Kevin L. (et al.)

    Pages 41-55

  • Defining the Stability of Multimeric Proteins

    Shriver, John W. (et al.)

    Pages 57-82

  • Protein–Protein and Ligand–Protein Interactions Studied by Analytical Ultracentrifugation

    Stafford, Walter F., III

    Pages 83-113

  • Monitoring Molecular Interactions by NMR

    Lipchock, James M. (et al.)

    Pages 115-134

Buy this book

eBook $139.00
price for USA in USD (gross)
  • ISBN 978-1-59745-367-7
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.00
price for USA in USD
  • ISBN 978-1-58829-954-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $179.00
price for USA in USD
  • ISBN 978-1-61737-855-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Protein Structure, Stability, and Interactions
Editors
  • John W. Shriver
Series Title
Methods in Molecular Biology
Series Volume
490
Copyright
2009
Publisher
Humana Press
Copyright Holder
Humana Press
eBook ISBN
978-1-59745-367-7
DOI
10.1007/978-1-59745-367-7
Hardcover ISBN
978-1-58829-954-3
Softcover ISBN
978-1-61737-855-3
Series ISSN
1064-3745
Edition Number
1
Number of Pages
X, 360
Number of Illustrations and Tables
135 b/w illustrations
Topics