Editors:
- Brings together all the methodology needed to perform human hepatocyte transplantation for the first time in one volume
- Key researchers cover all aspects of hepatocyte transplantation from bench to bedside
- Provides a practical basis for evaluating stem cell-derived hepatocytes for the treatment of liver disease in the future
Part of the book series: Methods in Molecular Biology (MIMB, volume 481)
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Table of contents (18 protocols)
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Front Matter
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Back Matter
About this book
Due to its efficacy in animal models, cellular therapy using human hepatocytes is being evaluated worldwide as an alternative to organ transplantation in patients with liver-based metabolic disease and acute liver failure. In Hepatocyte Transplantation: Methods and Protocols, an international panel of experts provide up-to-date laboratory and clinical techniques covering the many key areas necessary for successful transplantation, such as cryopreservation, quality assurance, detection of cell engraftment, and the future of the field with the development of foetal hepatoblasts and stem cell derived hepatocytes. Written in the highly successful Methods in Molecular Biology™ series format, the chapters in this volume present brief introductions to the material, lists of the necessary materials and reagents, readily reproducible, step-by-step laboratory protocols, and Notes sections which highlight tips on troubleshooting and avoiding known pitfalls.
Comprehensive and cutting-edge, Hepatocyte Transplantation: Methods and Protocols is an ideal guide for researchers setting out in the rapidly progressing field of hepatocyte transplantation, as well as those who already have experience with this new therapy for liver disease.
Editors and Affiliations
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King’s College Hospital, London, UK
Anil Dhawan
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School of Medicine, King’s College London, London, UK
Robin D. Hughes
Bibliographic Information
Book Title: Hepatocyte Transplantation
Book Subtitle: Methods and Protocols
Editors: Anil Dhawan, Robin D. Hughes
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-59745-201-4
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Humana Press 2009
Hardcover ISBN: 978-1-58829-883-6Published: 28 January 2009
eBook ISBN: 978-1-59745-201-4Published: 19 December 2008
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XVII, 231
Topics: Biochemistry, general, Cell Biology, Stem Cells