Cancer Drug Discovery and Development

Cancer Proteomics

From Bench to Bedside

Editors: Daoud, Sayed S. (Ed.)

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  • Comprehensive look at the use of proteomic strategies in cancer therapy
  • Covers all the latest technologies used in proteomics
  • Includes in-depth information on the human proteome and the role of the FDA in regulating the use of proteomics
  • The latest research on proteomics and tyrosine kinases, p53 signalling and tumor biomarkers
  • Discusses the future uses of proteomics in therapeutic individualization and target discovery
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eBook $149.00
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  • ISBN 978-1-59745-169-7
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Hardcover $279.99
price for USA in USD
  • ISBN 978-1-58829-858-4
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Softcover $199.99
price for USA in USD
  • ISBN 978-1-61737-807-2
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  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
About this book

Over the past 20 years or so, there have been tremendous advances in our understanding of how normal cells transform to cancer and the importance of signaling pathways in cancer initiation and progression. Therefore, proteomics technologies must be improved for more global analysis of protein content of cells, tissues and body fluids as well as the posttranslational modifications to allow for proper detections and validation. In Cancer Proteomics, the authors collectively provide the current status of proteomics in cancer therapy and offers the existing technologies used in proteomics that allow for protein profiling and for the identification of druggable targets in human samples. Mass spectrometry based protein characterization and protein microarrays hold great promise of predicting response to specific drugs in cancer therapy. Insightful to the reader with broad perspectives on topics related to the use of proteomic strategies in cancer therapy, Cancer Proteomics offers anticipated challenges that may arise from its application in daily practice.

Reviews

From the reviews:

"This is a comprehensive overview of the current state of knowledge in the area of cancer proteomics … . appropriate for cancer researchers of diverse specialties and clinicians conducting basic or clinical cancer research. … a book that provides a truly comprehensive look at the utility of proteomics from ‘bench to bedside.’ All chapters are well referenced and of appropriate length, and many contain helpful illustrations. … an excellent book that is appropriate for scientists and clinicians with an interest in cancer proteomics." (John D. Robertson, Doody’s Review Service, May, 2008)

"This book … provides the reader with a current perspective and anticipated uses of proteomic strategies in cancer therapy as well as basic cancer research. … the book provides a broad account of the area of cancer proteomics and adequately covers issues relevant to the use of proteomic strategies in clinical research. … The book would be of interest to clinicians and basic cancer researchers … who are already involved in, or who are considering the use of proteomics in their work." (JF Timms, British Journal of Cancer, Vol. 99 (4), 2008)


Table of contents (11 chapters)

Table of contents (11 chapters)
  • Current and Emerging Mass Spectrometry Instrumentation and Methods for Proteomic Analyses

    Pages 3-35

    Willard, Belinda (et al.)

  • Integration of Genomics and Proteomics in Dissecting p53 Signaling

    Pages 39-57

    Lee, Kyunghee (et al.)

  • Proteomic Profiling of Tyrosine Kinases as Pharmacological Endpoints for Targeted Cancer Therapy

    Pages 59-77

    Alaoui-Jamali, Moulay A. (et al.)

  • Oncoproteomics for Personalized Management of Cancer

    Pages 81-99

    Jain, K.K.

  • Application of Serum and Tissue Proteomics to Understand and Detect Solid Tumors

    Pages 101-120

    Annunziata, Christina M. (et al.)

Buy this book

eBook $149.00
price for USA in USD
  • ISBN 978-1-59745-169-7
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.99
price for USA in USD
  • ISBN 978-1-58829-858-4
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
Softcover $199.99
price for USA in USD
  • ISBN 978-1-61737-807-2
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
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Bibliographic Information

Bibliographic Information
Book Title
Cancer Proteomics
Book Subtitle
From Bench to Bedside
Editors
  • Sayed S. Daoud
Series Title
Cancer Drug Discovery and Development
Copyright
2008
Publisher
Humana Press
Copyright Holder
Humana Press
eBook ISBN
978-1-59745-169-7
DOI
10.1007/978-1-59745-169-7
Hardcover ISBN
978-1-58829-858-4
Softcover ISBN
978-1-61737-807-2
Series ISSN
2196-9906
Edition Number
1
Number of Pages
XII, 264
Number of Illustrations
5 illustrations in colour
Topics