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The Leydig Cell in Health and Disease

  • Book
  • © 2007

Overview

Editors:
  1. Anita H. Payne

    1. Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford

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  2. Matthew P. Hardy

    1. Center for Biomedical Research, Population Council, New York

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    You can also search for this editor in PubMed   Google Scholar

  • Explores current and future clinical applications of Leydig cell function in key cellular processes
  • Examines toxins and other environmental factors that interfere with Leydig cell function
  • Presents Leydig cell developments from a rigorous scientific application, with additional emphasis on clinical applications

Part of the book series: Contemporary Endocrinology (COE)

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About this book

Nearly ten years after they published the first book devoted entirely to the Leydig cell, Matthew Hardy and Anita Payne have collaborated again to provide a comprehensive study of this fascinating and important cell type. The Leydig Cell in Health and Disease presents all of the developments in our understanding of Leydig cell biology and explores a wide variety of current and potential clinical applications. All aspects of Leydig cell biology, development, regulation, and physiology are explored in thirty-one expertly written chapters. The Leydig Cell in Health and Disease explores topics of great interest to the private sector, including the possible application of steroidogenesis discoveries to androgen synthesis or suppressing Leydig cell function as a key mechnanism in the development of a male contraceptive. This in-depth volume is an invaluable resource for information on the science and application of Leydig cell biology and function.

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Keywords

Table of contents (30 chapters)

  1. Front Matter

    Pages i-xii
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  2. Historical

    1. Front Matter

      Pages 1-1
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    2. A History of Leydig Cell Research

      • A. Kent Christensen
      Pages 3-30

  3. Cell Biology

    1. Front Matter

      Pages 31-31
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    2. Structural and Histological Analysis of Leydig Cell Steroidogenic Function

      • Syed G. Haider, Gisela Servos, Nicole Tran
      Pages 33-45

    3. Fetal Leydig Cells

      • Humphrey Hung-Chang Yao, Ivraym Barsoum
      Pages 47-54

    4. Regulation of Leydig Cells During Pubertal Development

      • Renshan Ge, Matthew P. Hardy
      Pages 55-70

    5. The Human Leydig Cell

      • Frederick P. Prince
      Pages 71-89

    6. Dynamics of Leydig Cell Regeneration After EDS

      • Katja Teerds, Eddy Rijntjes
      Pages 91-116

    7. Aging and the Decline of Androgen Production

      • Haolin Chen, Andrew Midzak, Lin-di Luo, Barry R. Zirkin
      Pages 117-131

  4. Steroidogenesis

    1. Front Matter

      Pages 133-133
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    2. Regulation of Leydig Cell Cholesterol Metabolism

      • Salman Azhar, Eve Reaven
      Pages 135-148

    3. The Role of StAR in Leydig Cell Steroidogenesis

      • Douglas M. Stocco
      Pages 149-155

    4. Steroidogenic Enzymes in Leydig Cells

      • Anita H. Payne
      Pages 157-171

    5. Development of Leydig Cell Steroidogenesis

      • Peter J. O’Shaughnessy, Heather Johnston, Paul Joseph Baker
      Pages 173-179

    6. Peripheral Testosterone Metabolism

      • Daniel P. Sherbet, Richard J. Auchus
      Pages 181-188

    7. Leydig Cell Aromatase

      • Serge Carreau
      Pages 189-195

    8. The Role of Estrogen Sulfotransferase in Leydig Cells

      • Wen-Chao Song
      Pages 197-205

    9. Endocrinology of Leydig Cells in Nonmammalian Vertebrates

      • Kelly Bonner Engel, Gloria Vincz Callard
      Pages 207-224

  5. Regulation

    1. Front Matter

      Pages 225-225
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Reviews

From the reviews:

"Part of the Series Contemporary Endocrinology, this volume reviews in 5 parts and 30 chapters written by an international team aspects of Leydig cell biology, physiology and clinic. The book has many high quality illustrations, some in color. Of interest to endocrinologists and andrologists." (Pediatric Endocrinology Reviews, Vol. 5 (2), December, 2007)

Editors and Affiliations

  • Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford

    Anita H. Payne

  • Center for Biomedical Research, Population Council, New York

    Matthew P. Hardy

Bibliographic Information

  • Book Title: The Leydig Cell in Health and Disease

  • Editors: Anita H. Payne, Matthew P. Hardy

  • Series Title: Contemporary Endocrinology

  • DOI: https://doi.org/10.1007/978-1-59745-453-7

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Humana Press 2007

  • Hardcover ISBN: 978-1-58829-754-9Published: 15 June 2007

  • eBook ISBN: 978-1-59745-453-7Published: 28 October 2007

  • Series ISSN: 2523-3785

  • Series E-ISSN: 2523-3793

  • Edition Number: 1

  • Number of Pages: XII, 476

  • Number of Illustrations: 77 b/w illustrations, 2 illustrations in colour

  • Topics: Endocrinology, Cell Biology, Human Physiology

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