Cancer Drug Discovery and Development Transforming Growth Factor-Beta in Cancer Therapy

Transforming Growth Factor-Beta in Cancer Therapy, Volume I

Basic and Clinical Biology

Editors: Jakowlew, Sonia B. (Ed.)

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  • In-depth detail of basic concepts of TGF- ß in normal physiology and cancer pathobiology
  • Conveniently divided into three easy-to-follow parts
  • Companion volume details cancer treatments and therapies
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Hardcover $279.99
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Softcover $279.99
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  • ISBN 978-1-61737-735-8
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About this book

Transforming Growth Factor-ß in Cancer Therapy, Volumes 1 and 2, provide a compendium of findings about the role of transforming growth factor-ß (TGF-ß) in cancer treatment and therapy. The first volume, Basic and Clinical Biology, is divided into three parts. Part I presents basic concepts of transforming growth factor-ß signaling in normal physiology and cancer pathobiology. Part II investigates transforming growth factor-ß superfamily members in normal and tumor biology. Part III details transforming growth factor-ß in inflammation and fibrosis.

This volume’s companion, Cancer Treatment and Therapy, examines transforming growth factor-ß in several developing and advanced cancers and discusses methods of treatment and therapy. Together, Transforming Growth Factor-ß in Cancer Therapy, Volumes 1 and 2, provide researchers and clinicians with a comprehensive and cutting-edge reference for the findings about the role of transforming growth factor-ß in biology and cancer treatment.

Reviews

From the reviews:

"This volume provides a comprehensive review of TGF-beta regulation, signaling, and cellular function in both normal and tumor biology. … will be of use to individuals interested in the role of TGF-beta in the development of cancer and fibrosis. This will likely benefit readers interested in TGF-beta in the pathogenesis of disease … . also be a resource for those interested in the complex intracellular signaling cascades elicited by TGF-beta in normal and altered cells." (James P Luyendyk, Doody’s Review Service, May, 2008)


Table of contents (45 chapters)

Table of contents (45 chapters)
  • Component Hardware for Transforming Growth Factor-β Signal Transduction: TGF-β Ligands, TGF-β Receptors, and Smads

    Pages 3-21

    Jakowlew, Sonia B., PhD

  • TGF-β Signaling in Homeostasis and Cancer

    Pages 23-35

    Seoane, Joan, PhD

  • TGF-β Availability: Latent TGF-β and Latent TGF-β Binding Proteins

    Pages 37-55

    Todorovic, Vesna, PhD (et al.)

  • Biological Functions of Latent TGF-β-Binding Proteins and Activation of TGF-β

    Pages 57-75

    Hyytiäinen, Marko, PhD (et al.)

  • Regulators of Smad2/3 Transcription and Phosphorylation

    Pages 77-90

    Atfi, Azeddine, PhD (et al.)

Buy this book

eBook $219.00
price for USA in USD
  • ISBN 978-1-59745-292-2
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.99
price for USA in USD
  • ISBN 978-1-58829-714-3
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
Softcover $279.99
price for USA in USD
  • ISBN 978-1-61737-735-8
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
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Bibliographic Information

Bibliographic Information
Book Title
Transforming Growth Factor-Beta in Cancer Therapy, Volume I
Book Subtitle
Basic and Clinical Biology
Editors
  • Sonia B. Jakowlew
Series Title
Cancer Drug Discovery and Development
Copyright
2008
Publisher
Humana Press
Copyright Holder
Humana Press
eBook ISBN
978-1-59745-292-2
DOI
10.1007/978-1-59745-292-2
Hardcover ISBN
978-1-58829-714-3
Softcover ISBN
978-1-61737-735-8
Series ISSN
2196-9906
Edition Number
1
Number of Pages
XXIV, 735
Topics