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Cancer Drug Discovery and Development

Genomics and Pharmacogenomics in Anticancer Drug Development and Clinical Response

Editors: Innocenti, Federico (Ed.)

  • Comprehensive reference for researchers in the field of cancer pharmacogenomics and clinicians, from both academia and industry
  • Provides a collection of multi-disciplinary topics
  • Covers the most important aspects of pharmacogenomics applied to cancer patients
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Buy this book

eBook $179.00
price for USA in USD (gross)
  • ISBN 978-1-60327-088-5
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.99
price for USA in USD
  • ISBN 978-1-58829-646-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $229.99
price for USA in USD
  • ISBN 978-1-61737-694-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

The availability of new molecular approaches to the selection of drug therapy is an emerging need, as the traditional approach based on the evaluation of patient and tumor characteristics is clearly far from optimal. Many, and in most cases the majority of treated patients do not have significant benefits from the treatment while they often experience moderate to severe toxicities. In "Pharmacogenomics, Anticancer Drug Discovery, and Response," edited by Federico Innocenti, readers will find a series of chapters addressing the role of genomic information in cancer therapy and in drug development representing a unique source, as it describes experimental approaches, statistical strategies, and clinical examples of the application of genomic medicine in oncology. This book provides the most comprehensive body of knowledge on the role of genetic and genomic variation in the individualization of drug therapies in cancer patients.

Reviews

From the reviews:

"The chapters of this book, written by outstanding scientists in the field of cancer pharmacogenomics, clearly show how DNA information from both the host and the tumor should be taken into account for rational selection of drug therapies in cancer patients. … the book provides a comprehensive and in-depth view of the field of cancer pharmacogenomics. The book is informative for clinicians, for people involved in development of cancer therapeutics on industrial level, and any scientists who are interested in cancer biology." (C. Altaner, Neoplasma, June, 2009)

"The chapters of this book, written by outstanding scientists in the field of cancer pharmacogenomics … . the book provides a comprehensive and in-depth view of the field of cancer pharmacogenomics. The book is informative for clinicians, for people involved in development of cancer therapeutics on industrial level, and any scientists who are interested in cancer biology." (C. Altaner, Neoplasma, April, 2009)


Table of contents (21 chapters)

  • Toward the Realization of the Promise of Microarrays in Oncology

    Stickle, Natalie, MSc (et al.)

    Pages 3-18

  • Cell-Based Models to Identify Genetic Variants Contributing to Anticancer Drug Response

    Dolan, M. Eileen, PhD (et al.)

    Pages 19-31

  • Proteomic Analysis in Cancer Patients

    Kuramitsu, Yasuhiro, MD, PhD (et al.)

    Pages 33-45

  • MicroRNAs and Discovery of New Targets

    Tsuchiya, Soken, PharmD (et al.)

    Pages 47-56

  • Pharmacogenomics of the National Cancer Institute’s 60-Tumor Cell Panel

    Wallqvist, Anders, PhD (et al.)

    Pages 57-74

Buy this book

eBook $179.00
price for USA in USD (gross)
  • ISBN 978-1-60327-088-5
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.99
price for USA in USD
  • ISBN 978-1-58829-646-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $229.99
price for USA in USD
  • ISBN 978-1-61737-694-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Genomics and Pharmacogenomics in Anticancer Drug Development and Clinical Response
Editors
  • Federico Innocenti
Series Title
Cancer Drug Discovery and Development
Copyright
2009
Publisher
Humana Press
Copyright Holder
Humana Press
eBook ISBN
978-1-60327-088-5
DOI
10.1007/978-1-60327-088-5
Hardcover ISBN
978-1-58829-646-7
Softcover ISBN
978-1-61737-694-8
Series ISSN
2196-9906
Edition Number
1
Number of Pages
XIV, 378
Number of Illustrations
50 b/w illustrations, 3 illustrations in colour
Topics