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Methods in Molecular Medicine

Stroke Genomics

Methods and Reviews

Editors: Read, Simon J., Virley, David (Eds.)

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eBook $139.00
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  • ISBN 978-1-59259-836-6
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Hardcover $179.99
price for USA in USD
  • ISBN 978-1-58829-333-6
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  • Usually dispatched within 3 to 5 business days.
Softcover $179.99
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  • ISBN 978-1-61737-500-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Although numerous genomic studies of stroke have examined such factors as stroke inheritance, chromosomal loci of risk, preclinical models of stroke, and differential gene expression of brain injury, repair, and recovery, much work to determine the precise role of gene function in human neurological pathophysiology remains ahead. In Stroke Genomics: Methods and Reviews, leading experts in the field explore the pragmatic application of the tools of genomic and molecular biology research to the treatment of stroke. Providing the reader with cutting-edge reviews of clinical and preclinical genomics, the authors relate changes in gene expression to physiological end points-such as functional imaging paradigms-to produce a more holistic approach in which molecular biology goes hand in hand with stroke pathophysiology. Topics of special interest include stem cell transplantation, gene therapy, clinical gene/gene interaction studies, and cytokine drug discovery. Readily reproducible techniques are provided, along with ancillary methods (imaging, animal models, human genetic study design, and transgenic animal production) that can be effectively applied to gene discovery. The protocols follow the successful Methods in Molecular Biology™ series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.
Cutting-edge and highly practical, Stroke Genomics: Methods and Reviews shows how to successfully design, execute, and interpret preclinical and clinical molecular biological studies of stroke, work that will greatly advance its understanding, as well as rapid development of the next generation of stroke therapeutics.

Reviews

From the reviews:

"The protocols presented in Stroke Genomics: Methods and Reviews will greatly benefit scientists interested in the molecular biology as well as the genetic and genomic basis of strokes." - Journal of Chemical Neuroanatomy

"...very interesting and informative...an attractive and interesting overview of the different aspects of the current stroke research...can be recommended as a source of useful and up-to-date practical and theoretical information on stroke genetics and on stroke associated gene expression." - European Neurology

"This book gives the opportunity for experts in the field to explore the practical and experimental applications of genomic and molecular biology research to the treatment of stroke. … The book also indicates detailed methods for studying the molecular biology of stroke. … It can be recommended if one is interested in the basic scientific background that underlies central nervous system pathology … ." (J. V. Byrne, Neuroradiology, Vol. 47, 2005)


Table of contents (15 chapters)

Table of contents (15 chapters)

Buy this book

eBook $139.00
price for USA in USD (gross)
  • ISBN 978-1-59259-836-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.99
price for USA in USD
  • ISBN 978-1-58829-333-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $179.99
price for USA in USD
  • ISBN 978-1-61737-500-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Stroke Genomics
Book Subtitle
Methods and Reviews
Editors
  • Simon J. Read
  • David Virley
Series Title
Methods in Molecular Medicine
Series Volume
104
Copyright
2005
Publisher
Humana Press
Copyright Holder
Humana Press
eBook ISBN
978-1-59259-836-6
DOI
10.1385/1592598366
Hardcover ISBN
978-1-58829-333-6
Softcover ISBN
978-1-61737-500-2
Series ISSN
1543-1894
Edition Number
1
Number of Pages
X, 351
Number of Illustrations
65 b/w illustrations
Topics