The Skeleton

Biochemical, Genetic, and Molecular Interactions in Development and Homeostasis

Editors: Massaro, Edward J., Rogers, John M. (Eds.)

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About this book

The skeleton is a complex multifunctional system. In addition to its mechanical/structural support function, it is, as the major reservoir of calcium, intimately involved in intracellular signaling pathways of critical importance both in the complex process of development and the maintenance of physiologic homeostasis. It is also, as the major source of blood cells, a critical part of the circulatory, respiratory, and immune systems. In The Skeleton: Biochemical, Genetic, and Molecular Interactions in Development and Homeostasis, established biomedical researchers, developmental biologists, and clinical practitioners offer a cutting-edge survey of diverse critical issues in bone biology. Topics range from chondrogenesis, chondrocytes, and cartilage to skeletal dysmorphology, and include the control of skeletal development, osteoblastic cell differentiation, and bone induction, growth, remodeling, and mineralization. The authors focus on the biochemical, genetic, and molecular interactions that support the development and homeostasis of the skeleton. Their state-of-the-art understanding of bone physiology-and how it is modified throughout all the stages of life-offers novel approaches for improving the endurance of load-bearing implants, achieving life-long optimal bone strength, overcoming microgravity (space flight), and hastening the healing of fractures, osteotomies, and arthrodeses. Equally important are their insights into metaphyseal fractures in the aged, into the mechanism(s) of osteopenia and osteoporosis, and into how and why, during menopause, healthy women lose only bone adjacent to the marrow.
Authoritative and up-to-date, The Skeleton: Biochemical, Genetic, and Molecular Interactions in Development and Homeostasis offers biomedical and clinical researchers rapid access to the latest understanding of the biochemistry, physiology, pharmacology, genetics, molecular biology, developmental biology, and aging of the skeleton.

Reviews

"...a valuable book...Every substantial biomedical library should have this book." -Doody's Health Sciences Book Review Journal

"Very detailed, clinical and laden with biological terminology, which makes the preface a must for new readers." -E-STREAMS

"Authoritative and up-to-date... a cutting-edge survey of diverse critical issues in bone biology." - Clinical Laboratory International

Table of contents (26 chapters)

Table of contents (26 chapters)

Buy this book

eBook $149.00
price for USA in USD
  • ISBN 978-1-59259-736-9
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.99
price for USA in USD
  • ISBN 978-1-58829-215-5
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
Softcover $199.99
price for USA in USD
  • ISBN 978-1-61737-427-2
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
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Bibliographic Information

Bibliographic Information
Book Title
The Skeleton
Book Subtitle
Biochemical, Genetic, and Molecular Interactions in Development and Homeostasis
Editors
  • Edward J. Massaro
  • John M. Rogers
Copyright
2004
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-59259-736-9
DOI
10.1007/978-1-59259-736-9
Hardcover ISBN
978-1-58829-215-5
Softcover ISBN
978-1-61737-427-2
Edition Number
1
Number of Pages
XVIII, 428
Topics