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Chronic Lymphocytic Leukemia

Molecular Genetics, Biology, Diagnosis, and Management

  • Book
  • © 2004

Overview

Editors:
  1. Guy B. Faguet

    1. Section of Hematology/Oncology, Veterans Affairs Medical Center, Augusta, USA

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Part of the book series: Contemporary Hematology (CH)

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Table of contents (23 chapters)

  1. Front Matter

    Pages i-xiv
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  2. Introduction

    1. Front Matter

      Pages 1-1
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    2. The Natural History of CLL

      • Gerald E. Marti, Vincent Zenger
      Pages 3-54

  3. Biology and Genetics

    1. Front Matter

      Pages 55-55
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    2. Genetics of B-Cell Chronic Lymphocytic Leukemia

      • Stephan Stilgenbauer, Peter Lichter, Hartmut Döhner
      Pages 57-75

    3. Molecular Biology of Chronic Lymphocytic Leukemia

      • William G. Wierda
      Pages 77-94

    4. The Heterogeneous Origin of the B-CLL Cell

      • Terry Hamblin
      Pages 95-107

    5. Pathogenesis of Impaired Cellular Immune Function in CLL

      • Patrick B. Johnston, Neil E. Kay
      Pages 109-121

    6. Cytokines and Soluble Molecules in CLL

      • Enrica Orsini, Robin Foa
      Pages 123-142

  4. Clinical Aspects: Diagnosis

    1. Front Matter

      Pages 143-143
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  5. Clinical Aspects: Diagnosis

    1. Immunophenotypic Differential Diagnosis and Cell Cycle Analysis

      • Vonda K. Douglas, Raul C. Braylan
      Pages 145-161

  6. Clinical Aspects: Diagnosis

    1. Common Cytogenetic Abnormalities

      • Gunnar Juliusson
      Pages 163-171

    2. Immunophenotypic Diagnosis of Leukemic B-Cell Chronic Lymphoproliferative Disorders Other Than Chronic Lymphocytic Leukemia

      • Alberto Orfao, Julia Almeida, Maria Luz Sanchez, Jesus F. San Miguel
      Pages 173-190

  7. Clinical Aspects: Prognosis

    1. Front Matter

      Pages 191-191
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  8. Clinical Aspects: Prognosis

    1. Staging of Chronic Lymphocytic Leukemia

      • Kanti R. Rai, Niraj Gupta
      Pages 193-199

    2. Prognostic Indicators of Chronic Lymphocytic Leukemia

      • Francesc Bosch, Emili Montserrat
      Pages 201-215

  9. Clinical Aspects: Treatment

    1. Front Matter

      Pages 217-217
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  10. Clinical Aspects: Treatment

    1. Guidelines for Clinical Management of CLL

      • Guillaume Dighiero
      Pages 219-240

    2. Autologous and Allogeneic Transplantations for Chronic Lymphocytic Leukemia

      • Mauricette Michallet
      Pages 255-268

  11. Clinical Aspects: Treatment

    1. Chemotherapy of Chronic Lymphocytic Leukemia

      • Alessandra Ferrajoli, Michael J. Keating, Susan M. O’Brien
      Pages 241-254
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Keywords

About this book

A comprehensive and critical review of the latest scientific advances in our understanding of the molecular genetics and biology of CLL and their application to the best management of CLL. The authors focus on diagnosis, prognosis, multifaceted treatment options, and complications. Among the diverse treatments considered are chemotherapy, autologous and allogenic transplantations, monoclonal antibody therapy, immunotoxin therapy, gene therapy, and several new therapeutic strategies. Familial and juvenile chronic lymphocytic leukemia are also discussed.

Reviews

"This book will certainly be a very useful reference work for the practicing adult haematologist." - Pediatric Hematology Oncology

Editors and Affiliations

  • Section of Hematology/Oncology, Veterans Affairs Medical Center, Augusta, USA

    Guy B. Faguet

Bibliographic Information

  • Book Title: Chronic Lymphocytic Leukemia

  • Book Subtitle: Molecular Genetics, Biology, Diagnosis, and Management

  • Editors: Guy B. Faguet

  • Series Title: Contemporary Hematology

  • DOI: https://doi.org/10.1007/978-1-59259-412-2

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 2004

  • Hardcover ISBN: 978-1-58829-099-1Published: 30 November 2003

  • Softcover ISBN: 978-1-61737-355-8Published: 09 November 2010

  • eBook ISBN: 978-1-59259-412-2Published: 30 November 2003

  • Edition Number: 1

  • Number of Pages: XIV, 421

  • Topics: Hematology, Cancer Research

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