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Methods in Molecular Medicine

Blood'Brain Barrier

Biology and Research Protocols

Editors: Nag, Sukriti (Ed.)

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eBook $189.00
price for USA in USD (gross)
  • ISBN 978-1-59259-419-1
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.99
price for USA in USD
  • ISBN 978-1-58829-073-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $249.99
price for USA in USD
  • ISBN 978-1-61737-339-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Despite the fact that the breakdown of the blood-brain barrier occurs in many brain diseases and is an important factor in mortality, the molecular mechanisms involved in the breakdown are not completely understood. In The Blood-Brain Barrier: Biology and Research Protocols, leading researchers and clinician-scientists present state-of-the-art morphologic, permeability, transport, in vitro, and molecular techniques to study the workings of the blood-brain barrier in health and disease. Described in step-by-step detail, each proven method includes an explanation of the theoretical basis of the method, a discussion of its advantages and limitations, notes on avoiding pitfalls, and examples of results obtained using the technique. At the cutting edge are techniques to explore the genomics and proteomics of brain endothelium.
Comprehensive and state-of-the-art, The Blood-Brain Barrier: Biology and Research Protocols offers pharmacologists, physiologists, neuroscientists, neurosurgeons, and neurologists an array of powerful tools to isolate undiscovered molecules, deepen our understanding of their role in health and disease, and identify targets for future gene therapy and therapeutic intervention.

Reviews

"An outstanding addition to the field! The book is unique in its organization and ease of reading and use as research resource. In my view, this book will emerge as one of the more cited and critical sources of information for all researchers exploring the nature of the blood-brain barrier."-Doody's Health Science Book Review Journal

Table of contents (36 chapters)

  • Morphology and Molecular Properties of Cellular Components of Normal Cerebral Vessels

    Nag, Sukriti

    Pages 3-36

  • Studies of Cerebral Vessels by Transmission Electron Microscopy and Morphometry

    Nag, Sukriti

    Pages 37-50

  • Freeze-Fracture Studies of Cerebral Endothelial Tight Junctions

    Wolburg, Hartwig (et al.)

    Pages 51-66

  • Studies of Cerebral Endothelium by Scanning and High-Voltage Electron Microscopy

    Lossinsky, Albert S. (et al.)

    Pages 67-82

  • Detection of Endothelial/Lymphocyte Interaction in Spinal Cord Microvasculature by Intravital Videomicroscopy

    Engelhardt, Britta (et al.)

    Pages 83-93

Buy this book

eBook $189.00
price for USA in USD (gross)
  • ISBN 978-1-59259-419-1
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.99
price for USA in USD
  • ISBN 978-1-58829-073-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $249.99
price for USA in USD
  • ISBN 978-1-61737-339-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Blood'Brain Barrier
Book Subtitle
Biology and Research Protocols
Editors
  • Sukriti Nag
Series Title
Methods in Molecular Medicine
Series Volume
89
Copyright
2003
Publisher
Humana Press
Copyright Holder
Humana Press
eBook ISBN
978-1-59259-419-1
DOI
10.1385/1592594190
Hardcover ISBN
978-1-58829-073-1
Softcover ISBN
978-1-61737-339-8
Series ISSN
1543-1894
Edition Number
1
Number of Pages
XIV, 550
Topics