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In Vitro Neurotoxicology

Principles and Challenges

  • Book
  • © 2004

Overview

Part of the book series: Methods in Pharmacology and Toxicology (MIPT)

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Table of contents (12 protocols)

About this book

Well-respected leaders in the field of in vitro neurotoxicology take a fresh look at their own and other's work, critically and comparatively analyzing it across experimental systems and toxicants, and synthesizing essential principles for in vitro neurotoxicity testing. Neurotoxicants of significance to human health are emphasized, especially those for which metabolism and dose-responses are well well studied both in vivo and in vitro: lead, mercury, organophosphorous insecticides, polychlorinated biphenyls and dioxin, ethanol, and endogenous proteins. The goal is to set out new concepts and research directions that will hasten significant improvement in the methods and systems for in vitro neurotoxicity testing.

Reviews

"This book covers a wide range of topics, starting with a nice overview of the field of neurotoxicology. Moving on to the meat of the material, the effects of toxins on neural development, function, and degeneration are examined, using well studied neurotoxicants as examples. A thorough list of articles as well as an annotated reading list are valuable additions, making the book an excellent reference. This is a valuable reference for anyone studying the advances in neurotoxicology. It is concise and easy to comprehend, without sacrificing quality in the process. It is written by leaders in the field, ensuring the information is relevant and up-to-date."-Doody's Health Sciences Book Review Journal

"This is a useful book that updates new an improved in vitro methods to help further understanding neurotoxicology. The information presented is exciting, the methods proposed are often innovative, and readers will find a challenging glimpse into the future contributions their own research efforts can generate. Neurotoxicologists will find studying this volume rewarding and inspiring." - Vet Human Toxicol

"...a helpful and up to date book..." - BTS Newsletter

Editors and Affiliations

  • Department of Veterinary Anatomy and Public Health, Texas A&M University College of Veterinary Medicine, College Station

    Evelyn Tiffany-Castiglioni

  • Center for Environmental and Rural Health, College Station

    Evelyn Tiffany-Castiglioni

  • University of California, Davis

    Mannfred A. Hollinger

Bibliographic Information

  • Book Title: In Vitro Neurotoxicology

  • Book Subtitle: Principles and Challenges

  • Editors: Evelyn Tiffany-Castiglioni, Mannfred A. Hollinger

  • Series Title: Methods in Pharmacology and Toxicology

  • DOI: https://doi.org/10.1385/1592596517

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Humana Press 2004

  • Hardcover ISBN: 978-1-58829-047-2Published: 01 December 2003

  • Softcover ISBN: 978-1-61737-323-7Published: 09 November 2010

  • eBook ISBN: 978-1-59259-651-5Published: 06 February 2008

  • Series ISSN: 1557-2153

  • Series E-ISSN: 1940-6053

  • Edition Number: 1

  • Number of Pages: XV, 331

  • Topics: Pharmacology/Toxicology

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