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Methods in Molecular Biology

Cyclic Peptide Design

Editors: Goetz, Gilles (Ed.)

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  • Includes cutting-edge techniques
  • Provides detail essential for successful results
  • Contains key advice from the experts
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eBook $169.00
price for USA in USD (gross)
  • ISBN 978-1-4939-9504-2
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Hardcover $219.99
price for USA in USD
  • ISBN 978-1-4939-9503-5
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  • Usually dispatched within 3 to 5 business days.
About this book

This book covers strategies to improve cell permeability, intestinal permeability, and metabolic stability, which are the typical liabilities associated with cyclic peptides, to enhance protein-protein recognition, and to build upon nature’s cyclic peptides and macrocycles. Chapters also cover key peptide screening and display strategies, as well as important synthetic approaches towards cyclic and helical peptides. Cyclic peptides have become of significant importance as chemical tools in biology and drug discovery, since this class of chemicals has become a credible alternative source of new drug leads on par with traditional small molecules. As a part of the Methods in Molecular Biology series, this collection includes the kind of detail and implementation advice to aid researchers in the field. 
Authoritative and cutting-edge, Cyclic Peptide Design serves as a critical resource and go-to reference for researchers within the pharmaceutical industry, as well as scientists and students in the bioorganic, medicinal, and natural product chemistry fields.

Table of contents (15 chapters)

Table of contents (15 chapters)
  • Design Principles for Intestinal Permeability of Cyclic Peptides

    Pages 1-15

    Mathiowetz, Alan M.

  • Strategies to Enhance Metabolic Stabilities

    Pages 17-40

    Khatri, Bhavesh (et al.)

  • Designing Cell-Permeable Macrocyclic Peptides

    Pages 41-59

    Appiah Kubi, George (et al.)

  • Computational Methods for Studying Conformational Behaviors of Cyclic Peptides

    Pages 61-71

    Jiang, Fan (et al.)

  • Computational Opportunities and Challenges in Finding Cyclic Peptide Modulators of Protein–Protein Interactions

    Pages 73-95

    Duffy, Fergal (et al.)

Buy this book

eBook $169.00
price for USA in USD (gross)
  • ISBN 978-1-4939-9504-2
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.99
price for USA in USD
  • ISBN 978-1-4939-9503-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Cyclic Peptide Design
Editors
  • Gilles Goetz
Series Title
Methods in Molecular Biology
Series Volume
2001
Copyright
2019
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC, part of Springer Nature
eBook ISBN
978-1-4939-9504-2
DOI
10.1007/978-1-4939-9504-2
Hardcover ISBN
978-1-4939-9503-5
Series ISSN
1064-3745
Edition Number
1
Number of Pages
X, 332
Number of Illustrations
58 b/w illustrations, 80 illustrations in colour
Topics