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Methods in Molecular Biology

TRP Channels

Methods and Protocols

Editors: Ferrer-Montiel, Antonio, Hucho, Tim (Eds.)

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  • Includes cutting-edge techniques
  • Provides step-by-step detail essential for reproducible results
  • Contains key implementation advice from the experts
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eBook $109.00
price for USA in USD (gross)
  • ISBN 978-1-4939-9446-5
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Hardcover $199.99
price for USA in USD
  • ISBN 978-1-4939-9445-8
  • with online files
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book aims to provide a guide to researchers on how to work with Transient Receptor Potential (TRP) channels, describing current methodologies and protocols, and highlighting the challenges ahead that will require the development of new technologies. Articles cover a wide range of techniques, from structure to function, concluding with how to best to evaluate some of the in vivo function of TRP channels, particularly in regard to their involvement in hyperalgesia and allodynia. Also, the collection describes important and inspiring available tools that are currently being used to investigate the activity of these channels in vitro and in vivo in terms of their underlying protein structure, segueing into dealing with the generation of pharmacological tools to explore their in vivo activity and their involvement in cellular signaling pathways, which may be developed into drugs to treat diseases caused by channel dysfunction or hyperactivity. Written for the highly successful Methods in Molecular Biology series, chapters include the necessary detail and implementation advice to ensure successful results in the lab. 
Authoritative and practical, TRP Channels: Methods and Protocols is a useful set of methodologies for scientists seeking to better understand this vital family of channels.

Table of contents (14 chapters)

Table of contents (14 chapters)
  • Molecular Evolution Bioinformatics Toward Structural Biology of TRPV1-4 Channels

    Pages 1-21

    Doñate-Macián, Pau (et al.)

  • Expression, Purification, and Crystallization of the Transient Receptor Potential Channel TRPV6

    Pages 23-37

    Singh, Appu K. (et al.)

  • Cryo Electron Microscopy of TRP Channels

    Pages 39-50

    Samanta, Amrita (et al.)

  • Mass Spectrometry-Based Analysis of TRPP2 Phosphorylation

    Pages 51-64

    Dumit, Verónica I. (et al.)

  • Combining Structural Data with Computational Methodologies to Investigate Structure–Function Relationships in TRP Channels

    Pages 65-82

    Oakes, Victoria (et al.)

Buy this book

eBook $109.00
price for USA in USD (gross)
  • ISBN 978-1-4939-9446-5
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.99
price for USA in USD
  • ISBN 978-1-4939-9445-8
  • with online files
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
TRP Channels
Book Subtitle
Methods and Protocols
Editors
  • Antonio Ferrer-Montiel
  • Tim Hucho
Series Title
Methods in Molecular Biology
Series Volume
1987
Copyright
2019
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC, part of Springer Nature
eBook ISBN
978-1-4939-9446-5
DOI
10.1007/978-1-4939-9446-5
Hardcover ISBN
978-1-4939-9445-8
Series ISSN
1064-3745
Edition Number
1
Number of Pages
X, 238
Number of Illustrations
11 b/w illustrations, 58 illustrations in colour
Topics