Editors:
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key note and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 1983)
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Table of contents (17 protocols)
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Front Matter
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Detection, Quantification, and Isolation of Acetylated Protein Targets
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Front Matter
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Lysine Acetylation
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Front Matter
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Sirtuin Targets of Acetylation
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Front Matter
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Modulation of DNA Repair by Acetylation
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Front Matter
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DNA Interactive Proteins and Processing Enzymes Affected by Acetylation
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Front Matter
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About this book
The book focuses on the regulation of protein function and biological activity by the post-translational modification known as acetylation. Chapters detail a wide range of topics in protein acetylation dealing with pathways relevant to cellular homeostasis, gene expression, and DNA metabolism. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge, Protein Acetylation: Methods and Protocols aims to be an extremely valuable resource to novices and experts alike whose research takes them in the direction of characterizing regulatory switches in protein acetylation events, and how they are manifested in significant ways in diverse mechanisms biological systems.
Editors and Affiliations
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NIH Biomedical Research Center, National Institute on Aging, National Institutes of Health, Baltimore, USA
Robert M. Brosh, Jr.
Bibliographic Information
Book Title: Protein Acetylation
Book Subtitle: Methods and Protocols
Editors: Robert M. Brosh, Jr.
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-4939-9434-2
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC, part of Springer Nature 2019
Hardcover ISBN: 978-1-4939-9433-5Published: 14 May 2019
Softcover ISBN: 978-1-4939-9436-6Published: 14 August 2020
eBook ISBN: 978-1-4939-9434-2Published: 13 May 2019
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XIII, 310
Number of Illustrations: 12 b/w illustrations, 40 illustrations in colour
Topics: Protein Science, Gene Expression, Posttranslational Modification