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Methods in Molecular Biology

Calcium-Binding Proteins of the EF-Hand Superfamily

From Basics to Medical Applications

Editors: Heizmann, Claus W. (Ed.)

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  • Includes cutting-edge techniques
  • Provides step-by-step detail essential for reproducible results
  • Contains key implementation advice from the experts
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eBook $229.00
price for USA in USD (gross)
  • ISBN 978-1-4939-9030-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $299.99
price for USA in USD
  • ISBN 978-1-4939-9029-0
  • with online files
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This detailed volume explores protocols for studying the many facets of Ca2+-imaging, Ca2+-signaling, and Ca2+-binding along with background information on the principles and application of these techniques. The content of the book delves into 48 chapters including subjects such as data analysis and modern technologies to study calcium-binding and signaling in cells, the superfamily of calcium-binding proteins characterized by the EF-hand structural motif, as well as their use as diagnostic and prognostic biomarkers in Laboratory Medicine and novel therapeutic drug targets. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 
Authoritative and comprehensive, Calcium-Binding Proteins of the EF-Hand Superfamily: From Basics to Medical Applications presents state-of-the-art, lab-based methods and easy-to-follow protocols for daily use, making it interesting for basic and medical researchers, cell- and molecular biologists, clinicians, clinical chemists, and the diagnostic industry.

Table of contents (48 chapters)

Table of contents (48 chapters)
  • Using Data Mining to Explore Calmodulin Bibliography

    Pages 3-14

    Haiech, Jacques (et al.)

  • Deep Two-Photon Imaging In Vivo with a Red-Shifted Calcium Indicator

    Pages 15-26

    Birkner, Antje (et al.)

  • High-Resolution Calcium Imaging Method for Local Calcium Signaling

    Pages 27-39

    Diercks, Björn-Philipp (et al.)

  • Measurement of Contractility and Calcium Release in Cardiac Spheroids

    Pages 41-52

    Zuppinger, Christian

  • Simultaneous Recording of Subcellular Ca2+ Signals from the Cytosol and Sarco/Endoplasmic Reticulum: Compartmentalized Dye Loading, Imaging, and Analysis

    Pages 53-71

    Niggli, Ernst (et al.)

Buy this book

eBook $229.00
price for USA in USD (gross)
  • ISBN 978-1-4939-9030-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $299.99
price for USA in USD
  • ISBN 978-1-4939-9029-0
  • with online files
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Calcium-Binding Proteins of the EF-Hand Superfamily
Book Subtitle
From Basics to Medical Applications
Editors
  • Claus W. Heizmann
Series Title
Methods in Molecular Biology
Series Volume
1929
Copyright
2019
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC, part of Springer Nature
eBook ISBN
978-1-4939-9030-6
DOI
10.1007/978-1-4939-9030-6
Hardcover ISBN
978-1-4939-9029-0
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XIX, 779
Number of Illustrations
58 b/w illustrations, 117 illustrations in colour
Topics