Methods in Molecular Biology

Cellular Senescence

Methods and Protocols

Editors: Demaria, Marco (Ed.)

Free Preview
  • Includes cutting-edge methods and protocols 
  • Provides step-by-step detail essential for reproducible results 
  • Contains key notes and implementation advice from the experts
see more benefits

Buy this book

eBook $139.00
price for USA in USD (gross)
  • ISBN 978-1-4939-8931-7
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.99
price for USA in USD
  • ISBN 978-1-4939-8930-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book describes current methods for the identification and characterization of the major hallmarks of senescent cells. Chapters focus on the high heterogeneity of the senescence phenotypes, and techniques to induce and identify specific senescence programs. Additional chapters describe cellular and mouse models in which is possible to study the complex cell and non-cell autonomous functions of senescent cells.  Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

 Authoritative and cutting-edge, Cellular Senescence: Methods and Protocols aims to ensure successful results in the further study of this vital field.

Table of contents (20 chapters)

Table of contents (20 chapters)
  • Detecting Cellular Senescence in Reprogramming

    Cazin, Coralie (et al.)

    Pages 1-10

  • DNA Damage In Situ Ligation Followed by Proximity Ligation Assay (DI-PLA)

    Galbiati, Alessandro (et al.)

    Pages 11-20

  • Reactive Oxygen Species Detection in Senescent Cells

    Victorelli, Stella (et al.)

    Pages 21-29

  • Cellular Identification and Quantification of Senescence-Associated β-Galactosidase Activity In Vivo

    Childs, Bennett G. (et al.)

    Pages 31-38

  • Relative Human Telomere Length Quantification by Real-Time PCR

    Vasilishina, A. (et al.)

    Pages 39-44

Buy this book

eBook $139.00
price for USA in USD (gross)
  • ISBN 978-1-4939-8931-7
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.99
price for USA in USD
  • ISBN 978-1-4939-8930-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Cellular Senescence
Book Subtitle
Methods and Protocols
Editors
  • Marco Demaria
Series Title
Methods in Molecular Biology
Series Volume
1896
Copyright
2019
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC, part of Springer Nature
eBook ISBN
978-1-4939-8931-7
DOI
10.1007/978-1-4939-8931-7
Hardcover ISBN
978-1-4939-8930-0
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XII, 253
Number of Illustrations
7 b/w illustrations, 39 illustrations in colour
Topics