Methods in Molecular Biology

Gene Regulatory Networks

Methods and Protocols

Editors: Sanguinetti, Guido, Huynh-Thu, Van Anh (Eds.)

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About this book

This volume explores recent techniques for the computational inference of gene regulatory networks (GRNs). The chapters in this book cover topics such as methods to infer GRNs from time-varying data; the extraction of causal information from biological data; GRN inference from multiple heterogeneous data sets; non-parametric and hybrid statistical methods; the joint inference of differential networks; and mechanistic models of gene regulation dynamics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, descriptions of recently developed methods for GRN inference, applications of these methods on real and/ or simulated biological data, and step-by-step tutorials on the usage of associated software tools.
Cutting-edge and thorough, Gene Regulatory Networks: Methods and Protocols is an essential tool for evaluating the current research needed to further address the common challenges faced by specialists in this field.

Reviews

“The book covers a variety of computational and mathematical aspects related to the inference of gene regulatory networks. The style of the chapters seamlessly binds the comprehensive overview that recommended the book to junior researchers and the thorough description of topics, highlighting new direction of research, that would appeal to post-graduates and established researchers.” (Irina Ioana Mohorianu, zbMATH 1417.92005, 2019)

Table of contents (16 chapters)

Table of contents (16 chapters)
  • Gene Regulatory Network Inference: An Introductory Survey

    Pages 1-23

    Huynh-Thu, Vân Anh (et al.)

  • Statistical Network Inference for Time-Varying Molecular Data with Dynamic Bayesian Networks

    Pages 25-48

    Dondelinger, Frank (et al.)

  • Overview and Evaluation of Recent Methods for Statistical Inference of Gene Regulatory Networks from Time Series Data

    Pages 49-94

    Grzegorczyk, Marco (et al.)

  • Whole-Transcriptome Causal Network Inference with Genomic and Transcriptomic Data

    Pages 95-109

    Wang, Lingfei (et al.)

  • Causal Queries from Observational Data in Biological Systems via Bayesian Networks: An Empirical Study in Small Networks

    Pages 111-142

    White, Alex (et al.)

Buy this book

eBook $109.00
price for USA in USD (gross)
  • ISBN 978-1-4939-8882-2
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $149.99
price for USA in USD
  • ISBN 978-1-4939-8881-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Gene Regulatory Networks
Book Subtitle
Methods and Protocols
Editors
  • Guido Sanguinetti
  • Van Anh Huynh-Thu
Series Title
Methods in Molecular Biology
Series Volume
1883
Copyright
2019
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC, part of Springer Nature
eBook ISBN
978-1-4939-8882-2
DOI
10.1007/978-1-4939-8882-2
Hardcover ISBN
978-1-4939-8881-5
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XI, 430
Number of Illustrations
43 b/w illustrations, 71 illustrations in colour
Topics