Methods in Molecular Biology

Methionine Dependence of Cancer and Aging

Methods and Protocols

Editors: Hoffman, Robert M. (Ed.)

Free Preview
  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
see more benefits

Buy this book

eBook $169.00
price for USA in USD (gross)
  • ISBN 978-1-4939-8796-2
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.99
price for USA in USD
  • ISBN 978-1-4939-8795-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book explores the methionine dependence of cancer and its effects on aging, a great story of science that is not widely known. The chapters in this book describe the discovery of methionine dependence of cancer; the molecular basis for the increased methionine demand of cancer cells and tumors; the clinical application of methionine dependence of cancer in PET imaging with [11C]methionine; the development of methioninases as cancer drugs; the anti-aging and anti-diabetes effects of methionine restriction; and the future of targeting methionine in the body for the elimination of cancer and for the extension of a healthy life-span. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.


Cutting-edge and thorough, Methionine Dependence of Cancer and Aging: Methods and Protocols is an important resource for researchers and scientists wishing to pursue this exciting and vital area of study."


Table of contents (24 chapters)

Table of contents (24 chapters)
  • Methods to Study the Role of Methionine-Restricted Diet and Methioninase in Cancer Growth Control

    Chaturvedi, Shushma (et al.)

    Pages 1-12

  • Altered Methionine Metabolism in Cancer Cells

    Hoffman, Robert M. (et al.)

    Pages 13-26

  • Linkage of Methionine Dependence and Other Features of Malignancy

    Hoffman, Robert M. (et al.)

    Pages 27-36

  • Isolation and Characterization of Methionine-Independent Clones from Methionine-Dependent Cancer Cells

    Borrego, Stacey L. (et al.)

    Pages 37-48

  • Tumor-Specific S/G2-Phase Cell Cycle Arrest of Cancer Cells by Methionine Restriction

    Hoffman, Robert M. (et al.)

    Pages 49-60

Buy this book

eBook $169.00
price for USA in USD (gross)
  • ISBN 978-1-4939-8796-2
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.99
price for USA in USD
  • ISBN 978-1-4939-8795-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Methionine Dependence of Cancer and Aging
Book Subtitle
Methods and Protocols
Editors
  • Robert M. Hoffman
Series Title
Methods in Molecular Biology
Series Volume
1866
Copyright
2019
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC, part of Springer Nature
eBook ISBN
978-1-4939-8796-2
DOI
10.1007/978-1-4939-8796-2
Hardcover ISBN
978-1-4939-8795-5
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XII, 329
Number of Illustrations
46 b/w illustrations, 34 illustrations in colour
Topics