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Methods in Molecular Biology

Programmed Necrosis

Methods and Protocols

Editors: Ting, Adrian T. (Ed.)

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  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
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eBook $139.00
price for USA in USD (gross)
  • ISBN 978-1-4939-8754-2
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.99
price for USA in USD
  • ISBN 978-1-4939-8753-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $179.99
price for USA in USD
  • Customers within the U.S. and Canada please contact Customer Service at +1-800-777-4643, Latin America please contact us at +1-212-460-1500 (24 hours a day, 7 days a week).
  • Due: September 6, 2019
  • ISBN 978-1-4939-9384-0
  • Free shipping for individuals worldwide
About this book

This volume explores the latest techniques and approaches used to study this emerging form of cell death. The chapters in this book cover topics such as distinguishing necroptosis from apoptosis; detecting MLKL oligomerization during programmed necrosis; analyzing the RIPK3 necrosome complex; using RIPK1 kinase small molecule inhibitors in studying necroptosis; monitoring RIPK1 phosphorylation in the TNFR1 signaling complex; and assessing in vivo kidney cell death in glomerular injury. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Cutting-edge and thorough, Programmed Necrosis: Methods and Protocols is a valuable resource for technicians, graduate students, postdoctoral fellows, and other scientists who are pursuing studies in this field.

Table of contents (18 chapters)

Table of contents (18 chapters)
  • Tools in the Art of Studying Necroptosis

    Pages 1-9

    Ting, Adrian T.

  • Loss-of-Function RNAi Screen to Identify Necrosis-Signaling Molecules

    Pages 11-18

    Moquin, David Mark (et al.)

  • Chemical Library Screens to Identify Pharmacological Modulators of Necroptosis

    Pages 19-33

    Saleh, Danish (et al.)

  • Distinguishing Necroptosis from Apoptosis

    Pages 35-51

    Shlomovitz, Inbar (et al.)

  • Methods for Studying TNF-Mediated Necroptosis in Cultured Cells

    Pages 53-61

    Liu, Zikou (et al.)

Buy this book

eBook $139.00
price for USA in USD (gross)
  • ISBN 978-1-4939-8754-2
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.99
price for USA in USD
  • ISBN 978-1-4939-8753-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $179.99
price for USA in USD
  • Customers within the U.S. and Canada please contact Customer Service at +1-800-777-4643, Latin America please contact us at +1-212-460-1500 (24 hours a day, 7 days a week).
  • Due: September 6, 2019
  • ISBN 978-1-4939-9384-0
  • Free shipping for individuals worldwide
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Bibliographic Information

Bibliographic Information
Book Title
Programmed Necrosis
Book Subtitle
Methods and Protocols
Editors
  • Adrian T. Ting
Series Title
Methods in Molecular Biology
Series Volume
1857
Copyright
2018
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC, part of Springer Nature
eBook ISBN
978-1-4939-8754-2
DOI
10.1007/978-1-4939-8754-2
Hardcover ISBN
978-1-4939-8753-5
Softcover ISBN
978-1-4939-9384-0
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XI, 191
Number of Illustrations
30 b/w illustrations, 12 illustrations in colour
Topics