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Methods in Molecular Biology

Copy Number Variants

Methods and Protocols

Editors: Bickhart, Derek M. (Ed.)

  • Includes cutting-edge methods and protocols 
  • Provides step-by-step detail essential for reproducible results 
  • Contains key notes and implementation advice from the experts
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eBook $139.00
price for USA in USD (gross)
  • ISBN 978-1-4939-8666-8
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.99
price for USA in USD
  • ISBN 978-1-4939-8665-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This volume offers detailed step-by-step instructions to allow beginners and experts alike to run appropriate copy number variants (CNV) detection software on a dataset of choice and discern between false positive noise and true positive CNV signals. Chapters guide readers through single nucleotide polymorphism (SNP) chips, optical mapping assembly techniques, and current open-source programs specializing in CNV detection.  Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and cutting-edge, Copy Number Variants: Methods and Protocols aims to provide guidance to Bioinformaticians and Molecular Biologists who are interested in identifying copy number variants (CNV) with a wide variety of experimental media

Table of contents (17 chapters)

  • Identification of Copy Number Variants from SNP Arrays Using PennCNV

    Fang, Li (et al.)

    Pages 1-28

  • Using SAAS-CNV to Detect and Characterize Somatic Copy Number Alterations in Cancer Genomes from Next Generation Sequencing and SNP Array Data

    Zhang, Zhongyang (et al.)

    Pages 29-47

  • Statistical Detection of Genome Differences Based on CNV Segments

    Zhou, Yang (et al.)

    Pages 49-59

  • Whole-Genome Shotgun Sequence CNV Detection Using Read Depth

    Kahveci, Fatma (et al.)

    Pages 61-72

  • Read Depth Analysis to Identify CNV in Bacteria Using CNOGpro

    Brynildsrud, Ola

    Pages 73-81

Buy this book

eBook $139.00
price for USA in USD (gross)
  • ISBN 978-1-4939-8666-8
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.99
price for USA in USD
  • ISBN 978-1-4939-8665-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Copy Number Variants
Book Subtitle
Methods and Protocols
Editors
  • Derek M. Bickhart
Series Title
Methods in Molecular Biology
Series Volume
1833
Copyright
2018
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC, part of Springer Nature
eBook ISBN
978-1-4939-8666-8
DOI
10.1007/978-1-4939-8666-8
Hardcover ISBN
978-1-4939-8665-1
Series ISSN
1064-3745
Edition Number
1
Number of Pages
X, 206
Number of Illustrations
11 b/w illustrations, 25 illustrations in colour
Topics