Editors:
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 1828)
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Table of contents (37 protocols)
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Front Matter
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Basics and Introductions
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Front Matter
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In Vitro Evaluation of Exon Skipping for DMD
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Front Matter
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In Vivo Evaluation of Exon Skipping for DMD
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Front Matter
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About this book
This book presents a comprehensive collection of detailed state-of-the-art exon skipping and splices modulation protocols. Chapters detail 14 genetic diseases, AON-mediated therapies, and CRISPR/Cas9-mediated gene editing therapies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge, Exon Skipping and Inclusion Therapies: Methods and Protocols aims to help researchers initiate the development of next-generation therapies.
Editors and Affiliations
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Medical Genetics, University of Alberta, Edmonton, Canada
Toshifumi Yokota, Rika Maruyama
Bibliographic Information
Book Title: Exon Skipping and Inclusion Therapies
Book Subtitle: Methods and Protocols
Editors: Toshifumi Yokota, Rika Maruyama
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-4939-8651-4
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC, part of Springer Nature 2018
Hardcover ISBN: 978-1-4939-8650-7Published: 01 September 2018
Softcover ISBN: 978-1-4939-9354-3Published: 10 December 2019
eBook ISBN: 978-1-4939-8651-4Published: 31 August 2018
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XV, 569
Number of Illustrations: 26 b/w illustrations, 77 illustrations in colour
Topics: Human Genetics