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Methods in Molecular Biology

Exon Skipping and Inclusion Therapies

Methods and Protocols

Editors: Yokota, Toshifumi, Maruyama, Rika (Eds.)

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  • Includes cutting-edge methods and protocols 
  • Provides step-by-step detail essential for reproducible results 
  • Contains key notes and implementation advice from the experts
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eBook $149.00
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  • ISBN 978-1-4939-8651-4
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About this book

This book presents a comprehensive collection of detailed state-of-the-art exon skipping and splices modulation protocols. Chapters detail 14 genetic diseases, AON-mediated therapies, and CRISPR/Cas9-mediated gene editing therapies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and cutting-edge, Exon Skipping and Inclusion Therapies: Methods and Protocols aims to help researchers initiate the development of next-generation therapies.

Table of contents (37 chapters)

Table of contents (37 chapters)
  • Invention and Early History of Exon Skipping and Splice Modulation

    Pages 3-30

    Lim, Kenji Rowel Q. (et al.)

  • An Overview of Recent Advances and Clinical Applications of Exon Skipping and Splice Modulation for Muscular Dystrophy and Various Genetic Diseases

    Pages 31-55

    Rodrigues, Merryl (et al.)

  • Recent Advances and Clinical Applications of Exon Inclusion for Spinal Muscular Atrophy

    Pages 57-68

    Son, Hae-Won (et al.)

  • Nusinersen in the Treatment of Spinal Muscular Atrophy

    Pages 69-76

    Goodkey, Kara (et al.)

  • Tips to Design Effective Splice-Switching Antisense Oligonucleotides for Exon Skipping and Exon Inclusion

    Pages 79-90

    Maruyama, Rika (et al.)

Buy this book

eBook $149.00
price for USA in USD (gross)
  • ISBN 978-1-4939-8651-4
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.99
price for USA in USD
  • ISBN 978-1-4939-8650-7
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
Softcover $199.99
price for USA in USD
  • ISBN 978-1-4939-9354-3
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Exon Skipping and Inclusion Therapies
Book Subtitle
Methods and Protocols
Editors
  • Toshifumi Yokota
  • Rika Maruyama
Series Title
Methods in Molecular Biology
Series Volume
1828
Copyright
2018
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC, part of Springer Nature
eBook ISBN
978-1-4939-8651-4
DOI
10.1007/978-1-4939-8651-4
Hardcover ISBN
978-1-4939-8650-7
Softcover ISBN
978-1-4939-9354-3
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XV, 569
Number of Illustrations
26 b/w illustrations, 77 illustrations in colour
Topics

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