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Pre-Clinical and Clinical Methods in Brain Trauma Research

  • Book
  • © 2018

Overview

Editors:
  1. Amit K. Srivastava

    1. Department of Pediatric Surgery, McGovern Medical School, The University of Texas Health Sciences Center at Houston, Houston, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Charles S. Cox

    1. Department of Pediatric Surgery, McGovern Medical School, The University of Texas Health Sciences Center at Houston, Houston, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts

Part of the book series: Neuromethods (NM, volume 139)

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Table of contents (22 protocols)

  1. Front Matter

    Pages i-xiv
    Download chapter PDF

  2. Traumatic Brain Injury

    • Amit K. Srivastava, Charles S. Cox Jr.
    Pages 1-14

  3. Three-Dimensional In Vitro Brain Tissue Models

    • Min D. Tang-Schomer
    Pages 15-36

  4. Modeling Traumatic Brain Injury In Vitro

    • Daniel E. Bonder, Carolyn E. Keating, Namas Chandra, D. Kacy Cullen, Bryan J. Pfister
    Pages 37-69

  5. Drosophila Model to Study Chronic Traumatic Encephalopathy

    • Rojahne Azwoir, Liam Chen
    Pages 71-80

  6. Controlled Cortical Impact for Modeling Traumatic Brain Injury in Animals

    • Nicole Osier, C. Edward Dixon
    Pages 81-95

  7. Fluid Percussion Model of Traumatic Brain Injury

    • Rachel K. Rowe, Daniel Griffiths, Jonathan Lifshitz
    Pages 97-110

  8. Development of a Rodent Model of Closed Head Injury: The Maryland Model

    • Erik Hayman, Kaspar Kaledjian, Vladimir Gerzanich, J. Marc Simard
    Pages 111-121

  9. Rodent Model of Primary Blast-Induced Traumatic Brain Injury: Guidelines to Blast Methodology

    • Venkatasivasai Sujith Sajja, Peethambaram Arun, Stephen A. Van Albert, Joseph B. Long
    Pages 123-138

  10. Cognitive and Motor Function Assessments in Rodent Models of Traumatic Brain Injury

    • Danielle Scott, Kathryn E. Saatman
    Pages 139-154

  11. Pre-Procedural Considerations and Post-Procedural Care for Animal Models with Experimental Traumatic Brain Injury

    • Mary A. Robinson, Samer M. Jaber, Stacey L. Piotrowski, Thomas H. Gomez
    Pages 155-172

  12. Laser Capture Microdissection of Single Cells, Cell Populations, and Brain Regions Affected by Traumatic Brain Injury

    • Harris A. Weisz, Deborah R. Boone, Stacy L. Sell, Helen L. Hellmich
    Pages 173-190

  13. Rat Microglia Isolation and Characterization Using Multiparametric Panel for Flow Cytometric Analysis

    • Naama E. Toledano Furman, Karthik S. Prabhakara, Supinder Bedi, Charles S. Cox Jr., Scott D. Olson
    Pages 191-199

  14. The Principles of Experimental Design and the Determination of Sample Size When Using Animal Models of Traumatic Brain Injury

    • Michael F. W. Festing
    Pages 201-225

  15. Advanced Informatics Methods in Acute Brain Injury Research

    • Jude P. J. Savarraj, Mary F. McGuire, Ryan Kitagawa, Huimahn Alex Choi
    Pages 227-242

  16. Rapid Detection and Monitoring of Brain Injury Using Sensory-Evoked Responses

    • Jonathan A. N. Fisher, Cristin G. Welle
    Pages 243-256

  17. Advanced Neuroimaging Methods in Traumatic Brain Injury

    • Jenifer Juranek
    Pages 257-270

  18. Dynamic Contrast-Enhanced MRI for the Analysis of Blood-Brain Barrier Leakage in Traumatic Brain Injury

    • Qiang Shen, Timothy Q. Duong
    Pages 271-282

  19. Assessments for Quantifying Neuromotor Functioning After Repetitive Blast Exposure

    • Christopher K. Rhea, Nikita A. Kuznetsov, W. Geoffrey Wright, F. Jay Haran, Scott E. Ross, Josh L. Duckworth
    Pages 283-305

  20. Translingual Neurostimulation (TLNS): Perspective on a Novel Approach to Neurorehabilitation after Brain Injury

    • Yuri Danilov, Dafna Paltin
    Pages 307-327
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Keywords

About this book

This volume explores current viewpoints and knowledge gaps in the field of traumatic brain injury (TBI). The chapters in this book cover topics ranging from development of in vitro and animal TBI models, to diagnostic imaging and disease monitoring in patients. Designing pre-clinical and clinical trials is also discussed. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.


Practical and thorough, Pre-Clinical and Clinical Methods in Brain Trauma Research is a valuable resource for both scientists and clinical researchers interested in learning about important techniques and their applications in the field of TBI.


Reviews

“This is a well-organized book of neuromethods in brain trauma intended for trainees in the laboratory … . The combination of excellent reviews of experimental procedures, clinical information, and detailed protocols will be helpful for graduate students, postdocs and neurosurgery residents. Additionally, clinicians and clinician scientists involved in translational research should find this volume especially useful.” (Bruce G. Lyeth, Neurosurgery, Vol. 85 (1), July, 2019)

Editors and Affiliations

  • Department of Pediatric Surgery, McGovern Medical School, The University of Texas Health Sciences Center at Houston, Houston, USA

    Amit K. Srivastava, Charles S. Cox

Bibliographic Information

  • Book Title: Pre-Clinical and Clinical Methods in Brain Trauma Research

  • Editors: Amit K. Srivastava, Charles S. Cox

  • Series Title: Neuromethods

  • DOI: https://doi.org/10.1007/978-1-4939-8564-7

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media, LLC, part of Springer Nature 2018

  • Hardcover ISBN: 978-1-4939-8563-0Published: 29 June 2018

  • Softcover ISBN: 978-1-4939-9327-7Published: 10 December 2019

  • eBook ISBN: 978-1-4939-8564-7Published: 29 June 2018

  • Series ISSN: 0893-2336

  • Series E-ISSN: 1940-6045

  • Edition Number: 1

  • Number of Pages: XIV, 381

  • Number of Illustrations: 11 b/w illustrations, 74 illustrations in colour

  • Topics: Neurosciences

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