Methods in Molecular Biology

Progranulin

Methods and Protocols

Editors: Bateman, Andrew, Bennett, Hugh P.J., Cheung, Siu Tim (Eds.)

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  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
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eBook $169.00
price for USA in USD
  • ISBN 978-1-4939-8559-3
  • Digitally watermarked, DRM-free
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Hardcover $219.99
price for USA in USD
Softcover $219.99
price for USA in USD
About this book

This volume explores experimental strategies to study progranulin as a regulatory protein in biological and disease processes. The chapters in this book are divided into four parts: Part One is an introduction to the topic; Part Two looks at analytical and in vitro methods to study progranulin biology; Part Three discusses the role of progranulin in cancer; and Part Four describes the process of using animal models to study progranulin in health and disease. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Cutting-edge and thorough, Progranulin: Methods and Protocols is a valuable resource for experienced researchers who want to expand their studies of this field, and newcomers who want to begin including progranulin into their work.

Table of contents (22 chapters)

Table of contents (22 chapters)
  • A Brief Overview of Progranulin in Health and Disease

    Pages 3-15

    Bateman, Andrew (et al.)

  • Chromatographic Methods for the Purification of Granulin Peptides

    Pages 19-34

    Bateman, Andrew (et al.)

  • Methods for Expression and Purification of Biologically Active Recombinant Progranulin

    Pages 35-49

    Zhao, Chun Yu (et al.)

  • Large-Scale Generation of Recombinant Granulin Peptides in E. coli

    Pages 51-64

    Tolkatchev, Dmitri

  • Nuclear Magnetic Resonance Spectroscopy in Analysis of Granulin Three-Dimensional Structure and Cysteine Bridging

    Pages 65-80

    Tolkatchev, Dmitri

Buy this book

eBook $169.00
price for USA in USD
  • ISBN 978-1-4939-8559-3
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.99
price for USA in USD
Softcover $219.99
price for USA in USD
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Bibliographic Information

Bibliographic Information
Book Title
Progranulin
Book Subtitle
Methods and Protocols
Editors
  • Andrew Bateman
  • Hugh P.J. Bennett
  • Siu Tim Cheung
Series Title
Methods in Molecular Biology
Series Volume
1806
Copyright
2018
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC, part of Springer Nature
eBook ISBN
978-1-4939-8559-3
DOI
10.1007/978-1-4939-8559-3
Hardcover ISBN
978-1-4939-8557-9
Softcover ISBN
978-1-4939-9325-3
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XIII, 363
Number of Illustrations
23 b/w illustrations, 56 illustrations in colour
Topics