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Methods in Molecular Biology

Teratogenicity Testing

Methods and Protocols

Editors: Félix, Luís (Ed.)

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  • Includes cutting-edge methods and protocols for the study of teratogenicity testing and assessment
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
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eBook $219.00
price for USA in USD (gross)
  • ISBN 978-1-4939-7883-0
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.99
price for USA in USD
  • ISBN 978-1-4939-7882-3
  • with online files
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $279.99
price for USA in USD
  • ISBN 978-1-4939-9314-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This detailed book provides a compilation of laboratory techniques and tests to assess the risks to embryo-fetal development from drug exposure during early developmental stages. After an introduction to teratogenicity testing, the contents explore both in vitro and in vivo techniques in the study of the teratogenic and fetotoxic effects of drugs, as well as numerous animal-based teratology methods. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 
Authoritative and comprehensive, Teratogenicity Testing: Methods and Protocols describes methods that integrate a battery of tests that can be performed in cells, organs, tissues, and animal models for evaluating toxicity and/or the safety of compounds in early developmental stages with the goal of estimating, preventing, or minimizing the teratogenic potential of drugs.

Table of contents (34 chapters)

Table of contents (34 chapters)
  • An Overview of Teratology

    Pages 3-32

    Calado, Ana M. (et al.)

  • Teratology Study Guidelines: An Overview

    Pages 33-59

    Alves-Pimenta, Sofia (et al.)

  • Biological Concerns on the Selection of Animal Models for Teratogenic Testing

    Pages 61-93

    Alves-Pimenta, Sofia (et al.)

  • The Validated Embryonic Stem Cell Test with Murine Embryonic Stem Cells

    Pages 97-124

    Walker, Lauren M. (et al.)

  • Human Pluripotent Stem Cells to Assess Developmental Toxicity in the Osteogenic Lineage

    Pages 125-145

    Madrid, Joseph V. (et al.)

Buy this book

eBook $219.00
price for USA in USD (gross)
  • ISBN 978-1-4939-7883-0
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.99
price for USA in USD
  • ISBN 978-1-4939-7882-3
  • with online files
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $279.99
price for USA in USD
  • ISBN 978-1-4939-9314-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Teratogenicity Testing
Book Subtitle
Methods and Protocols
Editors
  • Luís Félix
Series Title
Methods in Molecular Biology
Series Volume
1797
Copyright
2018
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC, part of Springer Nature
eBook ISBN
978-1-4939-7883-0
DOI
10.1007/978-1-4939-7883-0
Hardcover ISBN
978-1-4939-7882-3
Softcover ISBN
978-1-4939-9314-7
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XV, 614
Number of Illustrations
23 b/w illustrations, 85 illustrations in colour
Topics