Methods in Molecular Biology

Phenotypic Screening

Methods and Protocols

Editors: Wagner, Bridget (Ed.)

  • Includes cutting-edge methods and protocols 
  • Provides step-by-step detail essential for reproducible results 
  • Contains key notes and implementation advice from the experts
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eBook $169.00
price for USA in USD (gross)
  • ISBN 978-1-4939-7847-2
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.99
price for USA in USD
  • ISBN 978-1-4939-7846-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This volume provides a better understanding of the advancements in phenotypic readouts and improved disease models that generate novel biological insights and recapitulate clinically relevant biology. Chapters focus on phenotypic screening, the use of human cell models, microscopic approaches, assays to measure fat accumulation in C. elegans, the threat response in zebrafish, and protein-protein interactions in plant growth and development. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical, Phenotypic Screening: Methods and Protocols aims to make phenotypic screening approaches more accessible to a wide array of researchers throughout the academic and biotech communities.

Table of contents (20 chapters)

  • Nutrient Stress Small-Molecule Screening Platform for Escherichia coli

    El Zahed, Sara S. (et al.)

    Pages 1-18

  • Validation and Development of an Escherichia coli Riboflavin Pathway Phenotypic Screen Hit as a Small-Molecule Ligand of the Flavin Mononucleotide Riboswitch

    Balibar, Carl J. (et al.)

    Pages 19-40

  • Phenotypic Screening of Small Molecules with Antimalarial Activity for Three Different Parasitic Life Stages

    Kato, Nobutaka (et al.)

    Pages 41-52

  • Phenotypic Screening for Inhibitors of a Mutant Thrombopoietin Receptor

    Ngo, Anna (et al.)

    Pages 53-66

  • A Cell-Based Assay for Mitotic Spindle Orientation

    Glaubke, Elina (et al.)

    Pages 67-75

Buy this book

eBook $169.00
price for USA in USD (gross)
  • ISBN 978-1-4939-7847-2
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.99
price for USA in USD
  • ISBN 978-1-4939-7846-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Phenotypic Screening
Book Subtitle
Methods and Protocols
Editors
  • Bridget Wagner
Series Title
Methods in Molecular Biology
Series Volume
1787
Copyright
2018
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC, part of Springer Nature
eBook ISBN
978-1-4939-7847-2
DOI
10.1007/978-1-4939-7847-2
Hardcover ISBN
978-1-4939-7846-5
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XII, 280
Number of Illustrations and Tables
16 b/w illustrations, 36 illustrations in colour
Topics