Happy holidays from us to you—get up to $30 off your next print or eBook! Shop now >>

Methods in Molecular Biology

Chromothripsis

Methods and Protocols

Editors: Pellestor, Franck (Ed.)

  • Includes cutting-edge methods and protocols for the study of chromothripsis
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
see more benefits

Buy this book

eBook $169.00
price for USA in USD (gross)
  • ISBN 978-1-4939-7780-2
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.99
price for USA in USD
  • ISBN 978-1-4939-7779-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This detailed book presents an up-to-date view on methods and experimental approaches developed to identify and explore the chromothripsis phenomenon. Beginning with a section exploring the genesis and impact of chromothripsis, the collection continues by covering the identification of chromothripsis, the causal mechanisms of chromothripsis, the bioinformatics tools for chromothripsis analysis, and experimental systems recently developed for the in vitro investigation of chromothripsis. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 
Authoritative and practical, Chromothripsis: Methods and Protocols serves as a vital resource for cell biologists, molecular biologists, cytogeneticists, and geneticists investigating chromothripsis, but also for students and researchers new to the field of chromothripsis and genomic instability.

Table of contents (22 chapters)

  • The Genomic Characteristics and Origin of Chromothripsis

    Marcozzi, Alessio (et al.)

    Pages 3-19

  • Clinical Consequences of Chromothripsis and Other Catastrophic Cellular Events

    Fukami, Maki, M.D., Ph.D. (et al.)

    Pages 21-33

  • Potential Role of Chromothripsis in the Genesis of Complex Chromosomal Rearrangements in Human Gametes and Preimplantation Embryo

    Pellestor, Franck (et al.)

    Pages 35-41

  • Chromothripsis and the Macroevolution Theory

    Pellestor, Franck

    Pages 43-49

  • Analysis of Chromothripsis by Combined FISH and Microarray Analysis

    MacKinnon, Ruth N.

    Pages 53-77

Buy this book

eBook $169.00
price for USA in USD (gross)
  • ISBN 978-1-4939-7780-2
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.99
price for USA in USD
  • ISBN 978-1-4939-7779-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Chromothripsis
Book Subtitle
Methods and Protocols
Editors
  • Franck Pellestor
Series Title
Methods in Molecular Biology
Series Volume
1769
Copyright
2018
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC, part of Springer Nature
eBook ISBN
978-1-4939-7780-2
DOI
10.1007/978-1-4939-7780-2
Hardcover ISBN
978-1-4939-7779-6
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XI, 367
Number of Illustrations
12 b/w illustrations, 73 illustrations in colour
Topics