Methods in Molecular Biology

Epigenome Editing

Methods and Protocols

Editors: Jeltsch, Albert, Rots, Marianne G. (Eds.)

  • Includes cutting-edge techniques for the study of epigenome editingProvides step-by-step detail essential for reproducible results
  • Contains key implementation advice from the experts
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eBook $129.00
price for USA in USD (gross)
  • ISBN 978-1-4939-7774-1
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.99
price for USA in USD
  • ISBN 978-1-4939-7773-4
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  • Usually dispatched within 3 to 5 business days.
About this book

This detailed book explores the concepts and applications of epigenome editing, as presented by leading scientists in the field. Beginning with some general and topical reviews, the collection continues by covering the design of DNA-binding devices, optimization of the effector domains, readout of epigenome marks, and approaches for delivery at the cellular and organismal level. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 
Authoritative and practical, Epigenome Editing: Methods and Protocols will be of great assistance to people new to the field but also to those already engaged, as epigenetic editing is still a relatively unexplored field with many issues to be resolved.

Table of contents (26 chapters)

  • Editing the Epigenome: Overview, Open Questions, and Directions of Future Development

    Rots, Marianne G. (et al.)

    Pages 3-18

  • Zinc Fingers, TALEs, and CRISPR Systems: A Comparison of Tools for Epigenome Editing

    Waryah, Charlene Babra (et al.)

    Pages 19-63

  • Designing Epigenome Editors: Considerations of Biochemical and Locus Specificities

    Sen, Dilara (et al.)

    Pages 65-87

  • Generation of TALE-Based Designer Epigenome Modifiers

    Nitsch, Sandra (et al.)

    Pages 89-109

  • Neuroepigenetic Editing

    Hamilton, Peter J. (et al.)

    Pages 113-136

Buy this book

eBook $129.00
price for USA in USD (gross)
  • ISBN 978-1-4939-7774-1
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.99
price for USA in USD
  • ISBN 978-1-4939-7773-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Epigenome Editing
Book Subtitle
Methods and Protocols
Editors
  • Albert Jeltsch
  • Marianne G. Rots
Series Title
Methods in Molecular Biology
Series Volume
1767
Copyright
2018
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC, part of Springer Nature
eBook ISBN
978-1-4939-7774-1
DOI
10.1007/978-1-4939-7774-1
Hardcover ISBN
978-1-4939-7773-4
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XIV, 482
Number of Illustrations
14 b/w illustrations, 69 illustrations in colour
Topics