Methods in Molecular Biology

CpG Islands

Methods and Protocols

Editors: Vavouri, Tanya, Peinado, Miguel A. (Eds.)

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  • Includes cutting-edge techniques for the study of CpG islands
  • Provides step-by-step detail essential for reproducible results
  • Contains key implementation advice from the experts
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  • ISBN 978-1-4939-7768-0
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Hardcover $169.99
price for USA in USD
  • ISBN 978-1-4939-7767-3
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Softcover $169.99
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  • Customers within the U.S. and Canada please contact Customer Service at +1-800-777-4643, Latin America please contact us at +1-212-460-1500 (24 hours a day, 7 days a week).
  • Due: April 15, 2019
  • ISBN 978-1-4939-9279-9
  • Free shipping for individuals worldwide
About this book

This detailed volume examines bioinformatic and molecular biological methods useful to identify and to explore the functions of CpG islands, key navigation points to understand gene regulation in fundamental processes such as development and cell differentiation as well as in diseases like cancer. Beginning with a historical perspective and important properties of CpG islands, the book continues with sections on computational and wet lab methods related to the study of DNA methylation, and in-depth protocols for the analysis of CpG island functional features including epigenetic profiling and chromatin interactions. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. 
Authoritative and practical, CpG Islands: Methods and Protocols aims to provide readers with the information and methodologies necessary to continue to decipher how a genome’s structure and organization contribute to regulate biological processes.

Table of contents (18 chapters)

Table of contents (18 chapters)
  • CpG Islands: A Historical Perspective

    Antequera, Francisco (et al.)

    Pages 3-13

  • Biochemical Identification of Nonmethylated DNA by BioCAP-Seq

    Long, Hannah K. (et al.)

    Pages 15-29

  • Prediction of CpG Islands as an Intrinsic Clustering Property Found in Many Eukaryotic DNA Sequences and Its Relation to DNA Methylation

    Gómez-Martín, Cristina (et al.)

    Pages 31-47

  • CpG Islands in Cancer: Heads, Tails, and Sides

    Ferreira, Humberto J. (et al.)

    Pages 49-80

  • Infinium DNA Methylation Microarrays on Formalin-Fixed, Paraffin-Embedded Samples

    Moran, Sebastian (et al.)

    Pages 83-107

Buy this book

eBook $129.00
price for USA in USD (gross)
  • ISBN 978-1-4939-7768-0
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.99
price for USA in USD
  • ISBN 978-1-4939-7767-3
  • with online files
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $169.99
price for USA in USD
  • Customers within the U.S. and Canada please contact Customer Service at +1-800-777-4643, Latin America please contact us at +1-212-460-1500 (24 hours a day, 7 days a week).
  • Due: April 15, 2019
  • ISBN 978-1-4939-9279-9
  • Free shipping for individuals worldwide
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Bibliographic Information

Bibliographic Information
Book Title
CpG Islands
Book Subtitle
Methods and Protocols
Editors
  • Tanya Vavouri
  • Miguel A. Peinado
Series Title
Methods in Molecular Biology
Series Volume
1766
Copyright
2018
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC, part of Springer Nature
eBook ISBN
978-1-4939-7768-0
DOI
10.1007/978-1-4939-7768-0
Hardcover ISBN
978-1-4939-7767-3
Softcover ISBN
978-1-4939-9279-9
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XI, 340
Number of Illustrations
9 b/w illustrations, 43 illustrations in colour
Topics