Methods in Molecular Biology

Metabolic Profiling

Methods and Protocols

Editors: Theodoridis, Georgios, Gika, Helen G., Wilson, Ian (Eds.)

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  • Includes cutting-edge methods and protocols
    Provides step-by-step detail essential for reproducible results
    Contains key notes and implementation advice from the experts

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  • ISBN 978-1-4939-7643-0
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About this book

This volume explores the different approaches and techniques used by researchers to study the recent challenges and developments in metabolic profiling. This book is divided into IV parts. Part I contains chapters that highlight basic concepts, such as experimental design, data treatment, metabolite identification, and harmonization. Part II describes experimental protocols for both targeted and untargeted metabolomics covering the basic analytical technologies: LC-MS, GC-MS, NMR and CE-MS. In addition the protocols describe methods for the study of tissues, feces, blood and other types of biological samples as well as the application of chemical derivatization for GC-MS. Parts III and IV present the use of metabolomics in the study of food, plants and the life sciences, with examples from the quest for the discovery of disease biomarkers, physical exercise omics and metabolic profiling of food, fruit and wine. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and thorough, Metabolic Profiling: Methods and Protocols is a valuable resource for researchers who are interested in expanding their knowledge of this rapidly developing field.

Table of contents (19 chapters)

Table of contents (19 chapters)
  • Metabolic Profiling: Status, Challenges, and Perspective

    Pages 3-13

    Gika, Helen G. (et al.)

  • Quality Control and Validation Issues in LC-MS Metabolomics

    Pages 15-26

    Begou, Olga (et al.)

  • Data Treatment for LC-MS Untargeted Analysis

    Pages 27-39

    Riccadonna, Samantha (et al.)

  • Bio- and Chemoinformatics Approaches for Metabolomics Data Analysis

    Pages 41-61

    Witting, Michael

  • HILIC-MS/MS Multi-Targeted Method for Metabolomics Applications

    Pages 65-81

    Virgiliou, Christina (et al.)

Buy this book

eBook $89.00
price for USA in USD
  • ISBN 978-1-4939-7643-0
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • Immediate eBook download after purchase and usable on all devices
  • Bulk discounts available
Hardcover $119.00
price for USA in USD
Softcover $119.00
price for USA in USD
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Bibliographic Information

Bibliographic Information
Book Title
Metabolic Profiling
Book Subtitle
Methods and Protocols
Editors
  • Georgios Theodoridis
  • Helen G. Gika
  • Ian Wilson
Series Title
Methods in Molecular Biology
Series Volume
1738
Copyright
2018
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC, part of Springer Nature
eBook ISBN
978-1-4939-7643-0
DOI
10.1007/978-1-4939-7643-0
Hardcover ISBN
978-1-4939-7642-3
Softcover ISBN
978-1-4939-9252-2
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XI, 291
Number of Illustrations
10 b/w illustrations, 26 illustrations in colour
Topics