Editors:
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 1726)
Buy it now
Buying options
Tax calculation will be finalised at checkout
Other ways to access
This is a preview of subscription content, log in via an institution to check for access.
Table of contents (16 protocols)
-
Front Matter
-
Back Matter
About this book
This volume covers the mechanisms of pRb inactivation detailing repressive mechanisms commonly associated to cancer, and representative of the experimentally relevant tests used in the establishment of cancer diagnosis and prognosis. Chapters contain protocols and in-depth discussions for commonly used experimental approaches to assess the status and function of components of the pRb pathway, including pRb itself, in cell lines and biological samples.Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, The Retinoblastoma Protein aims to serve as a guide to assist molecular cancer biologists in their search for understanding of the molecular functions of this preeminent tumorsuppressor.
Editors and Affiliations
-
Biochemistry and Cancer Biology Divisions Basic Science Department, Ponce Health Sciences University, Ponce, Puerto Rico
Pedro G. Santiago-Cardona
Bibliographic Information
Book Title: The Retinoblastoma Protein
Editors: Pedro G. Santiago-Cardona
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-4939-7565-5
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC 2018
Hardcover ISBN: 978-1-4939-7564-8Published: 22 February 2018
Softcover ISBN: 978-1-4939-8522-7Published: 04 June 2019
eBook ISBN: 978-1-4939-7565-5Published: 21 February 2018
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XI, 200
Number of Illustrations: 6 b/w illustrations, 32 illustrations in colour
Topics: Cancer Research